Schlemm's canal and collector channels as therapeutic targets

H Gong, A Francis - Surgical Innovations in Glaucoma, 2014 - Springer
Intraocular pressure (IOP) is maintained within a normal range from a dynamic balance
between aqueous humor formation and drainage. Dysfunctional aqueous drainage results …

Anatomy of the aqueous outflow drainage pathways

K Lam, M Lawlor - Minimally Invasive Glaucoma Surgery, 2021 - Springer
Lowering intraocular pressure (IOP) has been central to glaucoma care for over a century.
Minimally invasive glaucoma surgical (MIGS) devices are able to exploit different aspects of …

Microinvasive glaucoma surgery: a review of Schlemm's canal-based procedures

J Konopińska, K Lewczuk, J Jabłońska… - Clinical …, 2021 - Taylor & Francis
Microinvasive glaucoma surgery has gained popularity over the past decade. It can be
performed using three different mechanisms. In the present review, we focused on …

Schlemm's canal: the outflow 'vessel'

K Lewczuk, J Jabłońska, J Konopińska… - Acta …, 2022 - Wiley Online Library
In a healthy eye, the aqueous humour (AH) flows via the ciliary body and trabecular
meshwork into the collector channels, which carry it to the episcleral veins. In glaucoma, a …

Collector channels: role and evaluation in Schlemm's canal surgery

A M. Elhusseiny, EC Jamerson… - Current Eye …, 2020 - Taylor & Francis
Objectives 1) To elucidate the role of collector channels in the aqueous humor outflow
pathway 2) To suggest anatomic and functional methods of imaging collector channels in …

Micro-invasive glaucoma surgery–an interventional glaucoma revolution

M Shah - Eye and Vision, 2019 - Springer
The glaucoma surgical landscape has changed dramatically over the last decade with the
introduction and integration of micro-invasive glaucoma surgery (MIGS) techniques. These …

A novel Schlemm's canal scaffold: histologic observations

I Grierson, H Saheb, MY Kahook… - Journal of …, 2015 - journals.lww.com
Purpose: To assess the biocompatibility of a novel implant made of Nitinol (nickel-titanium
alloy), designed to improve aqueous humor outflow. Materials and Methods: In the first arm …

Ab interno Schlemm's canal surgery

BA Francis, H Akil, BB Bert - Glaucoma Surgery, 2017 - karger.com
In primary open-angle glaucoma, the site of greatest resistance to aqueous outflow is
thought to be the trabecular meshwork (TM) and inner wall of Schlemm's canal …

[HTML][HTML] Circumferential viscodilation of Schlemm's canal with a flexible microcannula during non-penetrating glaucoma surgery

B Cameron, M Field, S Ball, J Kearney - Digit J Ophthalmol, 2006 - legacy.djo.harvard.edu
Purpose: A pilot study was performed to evaluate the safety and performance of the flexible
Ophthalmic Microcannula (iScience Surgical Corporation, Menlo Park, CA) in accessing and …

Aqueous outflow: segmental and distal flow

SS Swaminathan, DJ Oh, MH Kang… - Journal of Cataract & …, 2014 - journals.lww.com
The elevated intraocular pressure (IOP) of primary open-angle glaucoma is caused by
impaired outflow of aqueous humor through the trabecular meshwork. Within the …