A method of rapidly differentiating lung tumor from healthy tissue is extraordinarily needed
for both the diagnosis and the intraoperative margin assessment. We assessed the ability of …

A clinically compatible fluorescence lifetime imaging microscopy (FLIM) system was
developed. The system was applied to intraoperative in vivo imaging of head and neck …

Objective Autofluorescence imaging (AFI) videobronchoscopy is a new endoscopic tool that
improves visualization of neoplastic changes in the bronchial mucosa. The major aim of our …

Fluorescence lifetime imaging (FLIM) depends on the fluorescence decay differences
between tissues to generate image contrast. In the present study FLIM has been applied to …

Objective evaluation of the performance of autofluorescence bronchoscopy based on
analysis of thin sections of the bronchus of resected lungs was performed and compared …

A compact clinically compatible fluorescence lifetime imaging microscopy (FLIM) system
was designed and built for intraoperative disease diagnosis and validated in vivo in a …

Intraoperative molecular imaging is a promising new technology with numerous applications
in lung cancer surgery. Accurate identification of small nodules and assessment of tumor …

Purpose During lung cancer surgery, it is very important to define tumor boundaries and
determine the surgical margin distance. In previous research, systemically application of …

Re-excision rates for breast cancer lumpectomy procedures are currently nearly 25% due to
surgeons relying on inaccurate or incomplete methods of evaluating specimen margins. The …

Fluorescence lifetime imaging (FLIm) is an optical spectroscopic imaging technique capable
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …