Early exposure to psychosocial adversity is among the most potent predictors of depression.
Because depression commonly emerges prior to adulthood, we must consider the …

Child abuse is associated with markedly elevated rates of major depression (MDD) in child,
adolescent, and adult cohorts. This article reviews preclinical (eg, animal) studies of the …

Exposure to adversity and stress early in development yields vulnerability to mental
illnesses throughout the lifespan. Growing evidence suggests that this vulnerability has …

Early adverse experiences are associated with heighted vulnerability for stress-related
psychopathology across the lifespan. While extensive work has investigated the effects of …

Interest in the effects of early adversity on children's development reflects contemporary
emphases on early experience in the behavioral sciences and plasticity in the …

Vulnerability to emotional disorders including depression derives from interactions between
genes and environment, especially during sensitive developmental periods. Adverse early …

Child abuse is associated with markedly elevated rates of major depression and other
psychiatric disorders in adulthood. This article reviews preclinical studies examining the …

The impact that stressful encounters have upon long-lasting behavioural phenotypes is
varied. Whereas a significant proportion of the population will develop “stress-related” …

The overarching objective is to review how early exposure to adversity interacts with
inflammation to alter brain maturation. Both adversity and inflammation are significant risk …

BackgroundWhile various conceptualizations of the link between childhood adversity and
later depression have been offered, most have not accounted for the possibility that early …