Purpose: Conventional audiometry, used to detect elevated hearing thresholds, is
insensitive to cochlear pathologies involving cochlear synapse degeneration in the absence …

PURPOSE: Recent studies suggest synaptic connections between hair cells and the
auditory nerve may be more vulnerable to noise-induced damage than the cochlear hair …

Purpose: Studies in rodents, and more recently humans, suggest that noise exposure can
cause permanent damage to synaptic ribbons between cochlear inner hair cells and …

For decades, we have presumed the death of hair cells and spiral ganglion neurons are the
main cause of hearing loss and difficulties understanding speech in noise, but new findings …

Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

Cochlear synaptopathy, or “hidden hearing loss,” refers to a loss of synapses between inner
hair cells and auditory nerve fibers, and affects primarily low-spontaneous-rate fibers that …

Objectives: The aim of this study was to investigate the possible association between
electrophysiological outcomes, speech perception in noise, as possible measures of …

Noise-induced cochlear synaptopathy has been demonstrated in numerous rodent studies.
In these animal models, the disorder is characterized by a reduction in amplitude of wave I of …

This study aimed to advance towards a clinical diagnostic method for detection of cochlear
synaptopathy with the hypothesis that synaptopathy should be manifested in elevated …

Hearing loss caused by noise exposure, ototoxic drugs, or aging results from the loss of
sensory cells, as reflected in audiometric threshold elevation. Animal studies show that loss …