Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

Gametocytes are the only form of the malaria parasite that is transmissible to the mosquito
vector. They are present at low levels in blood circulation and significant knowledge gaps …

Malaria elimination means cessation of parasite transmission. At present, the declining
malaria incidence in many countries has made elimination a feasible goal. Transmission …

Much of the epidemiology of Plasmodium falciparum in Sub-Saharan Africa focuses on the
prevalence patterns of asexual parasites in people of different ages, whereas the …

Sexual differentiation and parasite transmission are intimately linked in the life cycle of
malaria parasites. The specialized cells providing this crucial link are the Plasmodium …

It is the mature gametocytes of Plasmodium that are solely responsible for parasite
transmission from the mammalian host to the mosquito. They are therefore a logical target …

Background The use of molecular techniques has put in the spotlight the existence of a large
mass of malaria sub-microscopic infections among apparently healthy populations. These …

Gametocytes are the sexual stage of the malaria parasite and are essential for transmission
to the mosquito. Antimalarial drugs have been reported to affect gametocyte production in …

The most important function of any parasite is to secure transmission to new hosts. The
gametocyte, the stage which has become developmentally committed to the sexual cycle …

Background The transmission of malaria to mosquitoes depends on the presence of
gametocytes that circulate in the peripheral blood of infected human hosts. Sensitive …