The prognosis and treatment of bladder cancer have improved little in the past 20 years.
Bladder cancer remains a debilitating and often fatal disease, and is among the most costly …

Bladder cancer (urothelial cancer of the bladder) is the most common malignancy affecting
the urinary system with increasing incidence and mortality. Treatment of bladder cancer has …

Bladder cancer is the most common type of tumor in the urogenital system. Approximately
75% of patients with bladder cancer present with non‑muscle‑invasive cancer, which is …

Urothelial cell carcinoma (UCC) of the bladder is one of the most common malignancies
worldwide, causing considerable morbidity and mortality. It is unusual among the epithelial …

Cancer of the urinary bladder is often a result of exposure to chemical carcinogens. Models
of this disease have been developed by exposing rodents to N-butyl-N-(4-hydroxybutyl) …

Bladder cancer is a common malignancy in the urinary tract. Despite different therapeutic
options, recurrence and progression of urothelial carcinoma after treatment is not …

Preclinical knowledge of dysregulated pathways and potential biomarkers for urological
cancers has undergone limited translation into the clinic. Moreover, the low approval rate of …

There is a great need to improve the outlook for people facing urinary bladder cancer,
especially for patients with invasive urothelial carcinoma (InvUC) which is lethal in 50% of …

Bladder cancer is a common malignancy that has a relatively poor outcome. Lack of culture
models for the bladder epithelium (urothelium) hampers the development of new …

Several rodent models of bladder cancer development have been established. The aim of
this review article is to provide a critical assessment of different animal models available for …