Functional implication for myelin regeneration in recovery from ischaemic stroke | Brain | Oxford
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Ischaemic stroke causes neuron loss and long-term functional deficits. Unfortunately,
effective approaches to preserving neurons and promoting functional recovery remain …

Brain tissue undergoes substantial activity-dependent reorganisation after stroke due to
neuronal plasticity, leading to partial functional recovery in patients. Concurrent myelin …

Although the majority of phase II/III clinical trials of neuroprotective drugs have failed, recent
clinical trials of endovascular recanalization using mechanical thrombectomy were proved …

Introduction: Amongst strategies to repair the brain, myelin repair offers genuine cause for
optimism. Myelin, which sheaths most axons in the central nervous system (CNS), is vital for …

The recovery of the patient is the goal of the neuroscientists after a stroke. To achieve this
recovery, there is a crucial need for increasing the understanding of the pathophysiological …

Unraveling the pathology of stroke is a prerequisite for designing therapeutic strategies. It
was reported that myelin injury exceeded axonal loss in the peri-infarct region of rodent …

Till now, our understanding of neurovascular dysfunction in brain injuries was greatly
expanded. Emerging experimental investigations suggested vascular failure is one of the …

Stroke is the second to third leading cause of death and the main cause of severe, long-term
disability in adults. However, treatment is almost reduced to fibrinolysis, a therapy useful in a …

White matter stroke is a common clinical problem, which leads to distinct histological
changes that are different than immune-mediated demyelination. The temporal changes …