Despite recent advances in cancer immunotherapy, certain tumor types, such as
Glioblastomas, are highly resistant due to their tumor microenvironment disabling the anti …

Glioblastoma multiforme (GBM) is the most common and lethal brain tumor characterized by
a strongly immunosuppressive tumor microenvironment (TME) that represents a barrier also …

Recent studies have shown the importance of the dynamic tumor microenvironment (TME) in
high-grade gliomas (HGGs). In particular, myeloid cells are known to mediate …

Glioblastoma (GBM) is the most aggressive primary brain tumor, with ineffective anti-tumor
responses and a poor prognosis despite aggressive treatments. GBM immune …

Glioblastomas (GBMs) are the most common and aggressive primary brain tumors. Due to
their malignant growth and invasion into the brain parenchyma coupled with resistance to …

Macrophage targeting therapies have had limited clinical success in glioblastoma (GBM).
Further understanding the GBM immune microenvironment is critical for refining …

The Glioblastoma (GBM) immune microenvironment plays a critical role in tumor
development, progression, and prognosis. A comprehensive understanding of the intricate …

Glioblastoma is the most common form of primary brain tumour in adults. For more than a
decade, conventional treatment has produced a relatively modest improvement in the …

The mesenchymal subtype of glioblastoma is thought to be determined by both cancer cell-
intrinsic alterations and extrinsic cellular interactions, but remains poorly understood. Here …

Despite considerable recent advances in understanding and treating many other cancers,
malignant brain tumors remain associated with low survival or severe long-term sequelae …