Euglycaemic diabetic ketoacidosis as a complication of SGLT-2 inhibitors: epidemiology, pathophysiology, and treatment

E Sampani, P Sarafidis… - Expert Opinion on Drug …, 2020 - Taylor & Francis
Introduction Sodium-glucose co-transporters 2 (SGLT-2) inhibitors are a relatively novel
class of oral medications for the treatment of Type 2 Diabetes Mellitus, which lower plasma …

[HTML][HTML] Nephrology consultation for severe SGLT2 inhibitor-induced ketoacidosis in type 2 diabetes: case report

F Nappi, A La Verde, G Carfora, C Garofalo… - Medicina, 2019 - mdpi.com
Euglycemic diabetic ketoacidosis (euDKA) related to sodium-glucose cotransporter 2
inhibitor (SGLT2-I), despite being reported as consistent, though infrequent, adverse effect in …

Sodium-glucose cotransporter 2 inhibitors and the risk of diabetic ketoacidosis; from pathophysiology to clinical practice

D Patoulias, A Manafis, C Mitas… - … Current Drug Targets …, 2018 - ingentaconnect.com
Background: SGLT-2 inhibitors are a novel class of antidiabetic drugs, recently approved for
the treatment of patients with T2DM. Their cardioprotective and renoprotective action, along …

SGLT 2 inhibitors: a systematic review of diabetic ketoacidosis and related risk factors in the primary literature

KR Burke, CA Schumacher… - … : The Journal of Human …, 2017 - Wiley Online Library
Study Objective Currently only minimal information is available regarding risk factors for the
development of sodium glucose cotransporter‐2 inhibitor (SGLT 2i)‐related diabetic …

[HTML][HTML] Managing hospitalized patients taking SGLT2 inhibitors: Reducing the risk of euglycemic diabetic ketoacidosis

J Selwyn, AR Pichardo-Lowden - Diabetology, 2023 - mdpi.com
Sodium-glucose cotransporter-2 (SGLT2) inhibitors are emerging as an important therapy
not only for type 2 diabetes (T2DM), but also for heart disease and kidney disease. As these …

Practical considerations for the use of sodium–glucose co-transporter type 2 inhibitors in treating hyperglycemia in type 2 diabetes

KSL Lam, CC Chow, KCB Tan, RCW Ma… - Current Medical …, 2016 - Taylor & Francis
Sodium–glucose co-transporter type 2 (SGLT2) inhibitors are a new class of oral anti-
diabetic agents with a unique, insulin-independent mode of action. In patients with diabetes …

Euglycemic ketoacidosis as a complication of SGLT2 inhibitor therapy

BF Palmer, DJ Clegg - Clinical journal of the American Society of …, 2021 - journals.lww.com
Abstract Sodium-glucose cotransporter-2 (SGLT2) inhibitors are drugs designed to lower
plasma glucose concentration by inhibiting Na+-glucose–coupled transport in the proximal …

[HTML][HTML] Assessing the risk of ketoacidosis due to sodium-glucose cotransporter (SGLT)-2 inhibitors in patients with type 1 diabetes: a meta-analysis and meta …

G Musso, A Sircana, F Saba, M Cassader… - PLoS …, 2020 - journals.plos.org
Background Sodium-glucose cotransporter-2 (SGLT2) inhibitors (SGLT2i) showed benefits
in type 1 diabetes mellitus (T1DM), but the risk of diabetic ketoacidosis (DKA) limits their use …

SGLT2 inhibition in type 1 diabetes with diabetic kidney disease: potential cardiorenal benefits can outweigh preventable risk of diabetic ketoacidosis

H Liu, VS Sridhar, BA Perkins, J Rosenstock… - Current Diabetes …, 2022 - Springer
Abstract Purpose of Review The aim of this review is to summarize existing research
investigating the use of sodium glucose cotransporter-2 (SGLT2) inhibitors in patients with …

Insights into the recognition and management of SGLT2-inhibitor-associated ketoacidosis: it's not just euglycemic diabetic ketoacidosis

S Dizon, EJ Keely, J Malcolm, A Arnaout - Canadian journal of diabetes, 2017 - Elsevier
Insights Into the Recognition and Management of SGLT2-Inhibitor-Associated Ketoacidosis: It's
Not Just Euglycemic Diabetic Ketoacidosis - ScienceDirect Skip to main contentSkip to article …