Recombinant mucin biotechnology and engineering
S Park, JCH Kuo, HL Reesink, MJ Paszek - Advanced drug delivery reviews, 2023 - Elsevier
Mucins represent a largely untapped class of polymeric building block for biomaterials,
therapeutics, and other biotechnology. Because the mucin polymer backbone is genetically …
therapeutics, and other biotechnology. Because the mucin polymer backbone is genetically …
Design and Synthesis of Mucin‐Inspired Glycopolymers
Mucins are bottlebrush biopolymers that are glycoproteins on the surfaces of cells and as
hydrogels secreted inside and outside the body. Mucin function in biology includes cell‐cell …
hydrogels secreted inside and outside the body. Mucin function in biology includes cell‐cell …
Advances in mucin mimic synthesis and applications in surface science
LA Navarro, DL French, S Zauscher - Current Opinion in Colloid & Interface …, 2018 - Elsevier
Highlights•Mucins are a class of heavily glycosylated glycoproteins.•Mucin use is inhibited
by batch heterogeneity, motivating synthesis of mucin mimics.•Mucin mimics can be …
by batch heterogeneity, motivating synthesis of mucin mimics.•Mucin mimics can be …
Preparation and applications of artificial mucins in biomedicine
RE Detwiler, JR Kramer - Current Opinion in Solid State and Materials …, 2022 - Elsevier
Mucus is an essential barrier material that separates organisms from the outside world. This
slippery material regulates the transport of nutrients, drugs, gases, and pathogens toward …
slippery material regulates the transport of nutrients, drugs, gases, and pathogens toward …
Mirror Image Mucins and Thio Mucins with Tunable Biodegradation
VR Kohout, CL Wardzala… - Journal of the American …, 2023 - ACS Publications
Mucin glycoproteins are the major component of mucus and are integral to the cellular
glycocalyx. Mucins play diverse roles in health and disease, are an important element in …
glycocalyx. Mucins play diverse roles in health and disease, are an important element in …
Structural alterations of mucins are associated with losses in functionality
M Marczynski, K Jiang, M Blakeley… - …, 2021 - ACS Publications
Commercial mucin glycoproteins are routinely used as a model to investigate the broad
range of important functions mucins fulfill in our bodies, including lubrication, protection …
range of important functions mucins fulfill in our bodies, including lubrication, protection …
Synthesis and biomedical applications of mucin mimic materials
VR Kohout, CL Wardzala, JR Kramer - Advanced drug delivery reviews, 2022 - Elsevier
Mucin glycoproteins are the major component of mucus and coat epithelial cell surfaces
forming the glycocalyx. The glycocalyx and mucus are involved in the transport of nutrients …
forming the glycocalyx. The glycocalyx and mucus are involved in the transport of nutrients …
Advances in mucin biopolymer research: Purification, characterization, and applications
M Marczynski, B Winkeljann… - … for Biomedical and …, 2021 - Wiley Online Library
This book chapter highlights mucins as macromolecular components for liquids, coatings, or
hydrogels that seek an application in biomedical engineering. We summarize current …
hydrogels that seek an application in biomedical engineering. We summarize current …
Chemically tunable mucin chimeras assembled on living cells
JR Kramer, B Onoa, C Bustamante… - Proceedings of the …, 2015 - National Acad Sciences
Mucins are a family of secreted and transmembrane glycoproteins characterized by a
massive domain of dense O-glycosylation on serine and threonine residues. Mucins are …
massive domain of dense O-glycosylation on serine and threonine residues. Mucins are …
[HTML][HTML] Display of the human mucinome with defined O-glycans by gene engineered cells
Mucins are a large family of heavily O-glycosylated proteins that cover all mucosal surfaces
and constitute the major macromolecules in most body fluids. Mucins are primarily defined …
and constitute the major macromolecules in most body fluids. Mucins are primarily defined …