[HTML][HTML] Antitumor and immunomodulatory effects of polysaccharides from broken-spore of Ganoderma lucidum

PY Wang, XL Zhu, ZB Lin - Frontiers in pharmacology, 2012 - frontiersin.org
The antitumor and immunomodulatory activity of broken-spore of Ganodermalucidum
polysaccharides (Gl-BSP) were investigated in vivo and in vitro. It was showed that Gl-BSP …

Antitumor Activity and Underlying Mechanisms of Ganopoly, The Refined Polysaccharides Extracted from Ganoderma Lucidum, in Mice

Y Gao, H Gao, E Chan, W Tang, A Xu… - Immunological …, 2005 - Taylor & Francis
Ganopoly is an aqueous polysaccharide fraction extracted from G. lucidum by patented
biochemical technique and has been marketed as an over-the-counter product for chronic …

Ganoderma lucidum Polysaccharides: Immunomodulation and Potential Anti-Tumor Activities

Z Xu, X Chen, Z Zhong, L Chen… - The American journal of …, 2011 - World Scientific
Ganoderma lucidum (G. lucidum), a basidiomycete white rot fungus, has long been
prescribed to prevent and treat various human diseases, particularly in China, Japan, and …

Ganoderma lucidum polysaccharides antagonize the suppression on lymphocytes induced by culture supernatants of B16F10 melanoma cells

LX Sun, ZB Lin, XS Duan, J Lu, ZH Ge… - Journal of Pharmacy …, 2011 - academic.oup.com
Objectives Tumour cells produce factors such as interleukin 10 (IL-10), transforming growth
factor β 1 (TGF-β 1) and vascular endothelial growth factor (VEGF) that suppress the function …

Ganoderma lucidum polysaccharide (GLP) enhances antitumor immune response by regulating differentiation and inhibition of MDSCs via a CARD9-NF-κB-IDO …

Y Wang, X Fan, X Wu - Bioscience Reports, 2020 - portlandpress.com
A homogeneous polysaccharide (GLP), with an average molecular weight of 4.44× 104 Da,
was isolated and purified from the fruiting bodies of Ganoderma lucidum. In this work, we …

Characterization and immunostimulatory activity of a polysaccharide from the spores of Ganoderma lucidum

L Guo, J Xie, Y Ruan, L Zhou, H Zhu, X Yun… - International …, 2009 - Elsevier
Spores of Ganoderma lucidum contain a large amount of bioactive substances and have a
higher bioactivity than the fruit bodies of G. lucidum. However, ingredients from spores are …

Ganoderma lucidum Spore Polysaccharide Inhibits the Growth of Hepatocellular Carcinoma Cells by Altering Macrophage Polarity and Induction of Apoptosis

M Song, Z Li, H Gu, R Tang, R Zhang… - Journal of …, 2021 - Wiley Online Library
Background. Ganoderma lucidum has certain components with known pharmacological
effects, including strengthening immunity and anti‐inflammatory activity. G. lucidum seeds …

[HTML][HTML] Removing the sporoderm from the sporoderm-broken spores of Ganoderma lucidum improves the anticancer and immune-regulatory activity of the water …

L Fang, Q Zhao, C Guo, D Guo, Z Li, J Xu, C Guo… - Frontiers in …, 2022 - frontiersin.org
Plant-derived polysaccharides have demonstrated promising anti-cancer effects via immune-
regulatory activity. The aim of the current study was to compare the chemical property and …

Study on antitumor activity and mechanism of Ganoderma polysaccharides B

Q Zhang, Z Lin - Zhongguo Zhong xi yi jie he za zhi Zhongguo …, 1999 - europepmc.org
Methods Both in vivo and in vitro experiments were conducted in the study. Proliferation of
tumor cells was detected by MTT method, tumor necrosis factor alpha (TNF alpha) was …

Polysaccharides from sporoderm‑removed spores of Ganoderma lucidum induce apoptosis in human gastric cancer cells via disruption of autophagic flux

J Zhong, L Fang, R Chen, J Xu, D Guo… - Oncology …, 2021 - spandidos-publications.com
The sporoderm‑broken spores of Ganoderma lucidum (G. lucidum) polysaccharide (BSGLP)
have been demonstrated to inhibit carcinogenesis in several types of cancer. However, to …