[HTML][HTML] Analysis of the T Cell Response to Zika Virus and Identification of a Novel CD8+ T Cell Epitope in Immunocompetent Mice

RD Pardy, MM Rajah, SA Condotta, NG Taylor… - PLoS …, 2017 - journals.plos.org
Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family. Although ZIKV infection
is typically mild and self-limiting in healthy adults, infection has been associated with …

CD8+ T Cell Immune Response in Immunocompetent Mice during Zika Virus Infection

H Huang, S Li, Y Zhang, X Han, B Jia, H Liu… - Journal of …, 2017 - Am Soc Microbiol
Zika virus (ZIKV) infection causees neurologic complications, including Guillain-Barré
syndrome in adults and central nervous system (CNS) abnormalities in fetuses. We …

[HTML][HTML] Mapping and role of the CD8+ T cell response during primary Zika virus infection in mice

AE Ngono, EA Vizcarra, WW Tang, N Sheets, Y Joo… - Cell host & …, 2017 - cell.com
CD8+ T cells may play a dual role in protection against and pathogenesis of flaviviruses,
including Zika virus (ZIKV). We evaluated the CD8+ T cell response in ZIKV-infected …

[HTML][HTML] Characterization of a 2016 clinical isolate of Zika virus in non-human primates

XF Li, HL Dong, XY Huang, YF Qiu, HJ Wang… - …, 2016 - thelancet.com
Animal models are critical to understand disease and to develop countermeasures for the
ongoing epidemics of Zika virus (ZIKV). Here we report a non-human primate model using a …

Animal models of Zika virus infection, pathogenesis, and immunity

TE Morrison, MS Diamond - Journal of virology, 2017 - Am Soc Microbiol
Zika virus (ZIKV) is an emerging mosquito-transmitted flavivirus that now causes epidemics
affecting millions of people on multiple continents. The virus has received global attention …

[HTML][HTML] CD4+T cells mediate protection against Zika associated severe disease in a mouse model of infection

M Hassert, KJ Wolf, KE Schwetye, RJ DiPaolo… - PLoS …, 2018 - journals.plos.org
Zika virus (ZIKV) has gained worldwide attention since it emerged, and a global effort is
underway to understand the correlates of protection and develop diagnostics to identify rates …

[HTML][HTML] Characterization of lethal Zika virus infection in AG129 mice

MT Aliota, EA Caine, EC Walker… - PLoS neglected …, 2016 - journals.plos.org
Background Mosquito-borne Zika virus (ZIKV) typically causes a mild and self-limiting illness
known as Zika fever, which often is accompanied by maculopapular rash, headache, and …

[HTML][HTML] Broadly neutralizing activity of Zika virus-immune sera identifies a single viral serotype

KA Dowd, CR DeMaso, RS Pelc, SD Speer, ARY Smith… - Cell reports, 2016 - cell.com
Recent epidemics of Zika virus (ZIKV) have been associated with congenital malformation
during pregnancy and Guillain-Barré syndrome. There are two ZIKV lineages (African and …

[HTML][HTML] Zika virus pathogenesis and tissue tropism

JJ Miner, MS Diamond - Cell host & microbe, 2017 - cell.com
Although Zika virus (ZIKV) was isolated approximately 70 years ago, few experimental
studies had been published prior to 2016. The recent spread of ZIKV to countries in the …

Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality

S Maciejewski, TJ Ruckwardt, KM Morabito… - Science translational …, 2020 - science.org
The emergence of Zika virus (ZIKV) in the Americas stimulated the development of multiple
ZIKV vaccine candidates. We previously developed two related DNA vaccine candidates …