Osteoarthritis is a common cause of disability worldwide. Although commonly referred to as
a disease of the joint cartilage, osteoarthritis affects all joint tissues equally. The …

Osteoarthritis (OA) is the most common chronic disease of human joints. The basis of
pathologic changes involves all the tissues forming the joint; already, at an early stage, it has …

A joint is the point of connection between two bones in our body. Inflammation of the joint
leads to several diseases, including osteoarthritis, which is the concern of this review …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic systemic
inflammation causing progressive joint damage that can lead to lifelong disability. The …

[Frontiers in Bioscience 4, d694-703, October 15, 1999] 694 CYTOKINES AND THEIR ROLE IN
THE PATHOPHYSIOLOGY OF OSTEOARTHRITIS Jo Page 1 [Frontiers in Bioscience 4 …

Even though osteoarthritis (OA) is mainly considered as a degradative condition of the
articular cartilage, there is increasing body of data demonstrating the involvement of all …

Osteoarthritis (OA) is associated with cartilage destruction, subchondral bone remodeling
and inflammation of the synovial membrane, although the etiology and pathogenesis …

OBJECTIVE:: The integrity of articular cartilage is maintained by the balance between
cytokine-driven anabolic and catabolic processes. Unregulated or excess influences of …

Structural damage of cartilage and bone tissue is a hallmark of rheumatoid arthritis (RA).
The resulting joint destruction constitutes one of the major disease consequences for …

The pathogenesis of osteoarthritis involves multiple etiologies, including mechanical,
biochemical, and genetic factors that contribute to the imbalance in the synthesis and …