Immune persistence of an inactivated poliovirus vaccine derived from the Sabin strain: a 10-year follow-up of a phase 3 study

L Ma, Z Ying, W Cai, J Wang, J Zhou, H Yang… - …, 2023 - thelancet.com
Background In a previous phase 3 clinical trial, we showed that an inactivated poliovirus
vaccine derived from the Sabin strain (sIPV) can induce neutralising antibodies against …

Immunogenicity and immune persistence in 4-year-old children completing four doses of Sabin strain or wild strain inactivated poliovirus vaccine: A phase IV, open …

K Chu, Y Li, D Yu, Y Song, S Liu, F Xue, Y Shan… - Vaccine, 2023 - Elsevier
Background Sabin strain inactivated poliovirus vaccine (hereinafter as “sIPV”) has been
marketed globally in recent years, and more data on its immune persistence are needed …

Immunogenicity and safety of different sequential schedules of Sabin strain-based inactivated poliovirus vaccination: A randomized, controlled, open-label, phase IV …

S Yan, H Chen, Z Zhang, S Chang, Y Xiao, L Luo… - Vaccine, 2020 - Elsevier
Background The immunogenicity and safety of the sequential schedule of Sabin strain-
based inactivated poliovirus vaccine (sIPV) and bivalent oral poliovirus vaccine (bOPV) …

Phase 3 trial of a Sabin strain–based inactivated poliovirus vaccine

G Liao, R Li, C Li, M Sun, S Jiang, Y Li… - The Journal of …, 2016 - academic.oup.com
Background The development of a Sabin strain–based inactivated poliovirus vaccine (Sabin-
IPV) is imperative to protecting against vaccine-associated paralytic poliomyelitis in …

Safety and immunogenicity of inactivated poliovirus vaccine made from Sabin strains: a phase II, randomized, positive-controlled trial

G Liao, R Li, C Li, M Sun, Y Li, J Chu… - Journal of Infectious …, 2012 - academic.oup.com
Abstract Background. The production of Sabin inactivated poliovirus vaccine (IPV) can
reduce biosafety requirements in the posteradication/post–oral poliovirus vaccine (OPV) era …

[HTML][HTML] Decay of Sabin inactivated poliovirus vaccine (IPV)-boosted poliovirus antibodies

S Resik, A Tejeda, M Fonseca, C Sein, LH Hung… - Trials in …, 2015 - Elsevier
Introduction We conducted a follow-on study to a phase I randomized, controlled trial
conducted in Cuba, 2012, to assess the persistence of poliovirus antibodies at 21–22 …

Immune serum from sabin inactivated poliovirus vaccine immunization neutralizes multiple individual wild and vaccine-derived polioviruses

M Sun, C Li, W Xu, G Liao, R Li, J Zhou… - Clinical Infectious …, 2017 - academic.oup.com
Background. A Sabin strain–based inactivated poliomyelitis vaccine (Sabin-IPV) is the
rational option for completely eradicating poliovirus transmission. The neutralizing capacity …

Safety and immunogenicity of a new Sabin inactivated poliovirus vaccine candidate produced on the PER. C6® cell-line: a phase 1 randomized controlled trial in …

I Leroux-Roels, G Leroux-Roels… - Human Vaccines & …, 2021 - Taylor & Francis
This first-in-human study (NCT03032588), conducted in Belgium, evaluated a new
inactivated poliovirus vaccines (IPV) candidate based on Sabin poliovirus strains grown on …

Safety and immunogenicity of a new inactivated polio vaccine made from sabin strains: a randomized, double-blind, active-controlled, phase 2/3 seamless study

MR Capeding, GD Gomez-Go… - The Journal of …, 2022 - academic.oup.com
Background A new inactivated polio vaccine made from Sabin strains (sIPV) was developed
as part of the global polio eradication initiative. Methods This randomized, double-blind …

Safety and immunogenicity of inactivated poliovirus vaccine made from Sabin strains: A phase II, randomized, dose-finding trial

K Chu, Z Ying, L Wang, Y Hu, J Xia, L Chen, J Wang… - Vaccine, 2018 - Elsevier
Background In order to completely eradicate polio caused by wild poliovirus infection as well
as vaccine-associated paralytic polio (VAPP), Sabin inactivated poliovirus vaccine (sIPV) …