Zbtb16 regulates social cognitive behaviors and neocortical development

N Usui, S Berto, A Konishi, M Kondo, G Konopka… - Translational …, 2021 - nature.com
Zinc finger and BTB domain containing 16 (ZBTB16) play the roles in the neural progenitor
cell proliferation and neuronal differentiation during development, however, how the function …

Neurodevelopmental disorder-associated ZBTB20 gene variants affect dendritic and synaptic structure

KA Jones, Y Luo, L Dukes-Rimsky, DP Srivastava… - PloS one, 2018 - journals.plos.org
Dendritic spine morphology and dendritic arborization are key determinants of neuronal
connectivity and play critical roles in learning, memory and behavior function. Recently …

Biallelic missense variants in ZBTB11 can cause intellectual disability in humans

Z Fattahi, TI Sheikh, L Musante… - Human molecular …, 2018 - academic.oup.com
Exploring genes and pathways underlying intellectual disability (ID) provides insight into
brain development and function, clarifying the complex puzzle of how cognition develops. As …

Hippocampus-like corticoneurogenesis induced by two isoforms of the BTB-zinc finger gene Zbtb20 in mice

JV Nielsen, FH Nielsen, R Ismail, J Noraberg… - 2007 - journals.biologists.com
Hippocampus-associated genes that orchestrate the formation of the compact stratum
pyramidale are largely unknown. The BTB (broad complex, tramtrack, bric-a-brac)-zinc …

Knockout Zbtb33 gene results in an increased locomotion, exploration and pre-pulse inhibition in mice

AV Kulikov, VS Korostina, EA Kulikova… - Behavioural Brain …, 2016 - Elsevier
The Zbtb33 gene encodes the Kaiso protein—a bimodal transcriptional repressor. Here, the
effects of Zbtb33 gene disruption on the brain and behaviour of the Kaiso-deficient (KO) and …

Inactivation of BRD7 results in impaired cognitive behavior and reduced synaptic plasticity of the medial prefrontal cortex

Y Xu, W Cao, M Zhou, C Li, Y Luo, H Wang… - Behavioural Brain …, 2015 - Elsevier
BRD7 is a bromodomain-containing protein (BCP), and recent evidence implicates the role
of BCPs in the initiation and development of neurodevelopmental disorders. However, few …

A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors

D Zou, C McSweeney, A Sebastian, DJ Reynolds… - Neural …, 2015 - Springer
Background Nonsense mediated mRNA decay (NMD) is an RNA surveillance mechanism
that controls RNA stability and ensures the speedy degradation of erroneous and …

ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2

MJ Girgenti, JJ LoTurco, BJ Maher - PloS one, 2012 - journals.plos.org
ZNF804a was identified by a genome-wide association study (GWAS) in which a single
nucleotide polymorphism (SNP rs1344706) in ZNF804a reached genome-wide statistical …

Zbtb20 promotes astrocytogenesis during neocortical development

M Nagao, T Ogata, Y Sawada, Y Gotoh - Nature communications, 2016 - nature.com
Multipotent neural precursor cells (NPCs) generate astrocytes at late stages of mammalian
neocortical development. Many signalling pathways that regulate astrocytogenesis directly …

Regulation of hippocampus‐dependent memory by the zinc finger protein Zbtb20 in mature CA1 neurons

A Ren, H Zhang, Z Xie, X Ma, W Ji… - The Journal of …, 2012 - Wiley Online Library
Key points• Zinc finger and BTB domain‐containing protein 20 (Zbtb20) plays a critical role
in hippocampal development.• In the present study, we generated mutant mice in which …