Toll‐like receptors: The role in bladder cancer development, progression and immunotherapy

S Ohadian Moghadam… - Scandinavian journal of …, 2019 - Wiley Online Library
Bladder cancer is one of the leading causes of death worldwide. The main immune
mechanisms which lead to bladder cancer development or treatment outcomes have yet to …

Toll-like receptors in urothelial cells—targets for cancer immunotherapy

H LaRue, C Ayari, A Bergeron, Y Fradet - Nature Reviews Urology, 2013 - nature.com
Toll-like receptors (TLRs) have an important role in the activation of both innate and
adaptive immunity in response to pathogens and danger signals. These receptors are …

Toll-like receptors in normal and malignant human bladders

C Ayari, A Bergeron, H LaRue, C Ménard, Y Fradet - The Journal of urology, 2011 - Elsevier
PURPOSE: Toll-like receptors have a major role in the innate immune response. They are
expressed by immune cells and some epithelial cells. To study the role of urothelial cells in …

TLR4-and TLR9-dependent effects on cytokines, cell viability, and invasion in human bladder cancer cells

PJ Olbert, C Kesch, M Henrici, FS Subtil… - … oncology: seminars and …, 2015 - Elsevier
Objectives Adjuvant immunotherapy of bladder cancer by instillation of bacillus Calmette-
Guérin (BCG) is highly recommended within certain groups of non–muscle-invasive stages …

Toll-like receptors: cost or benefit for cancer?

T Matijevic, J Pavelic - Current pharmaceutical design, 2010 - ingentaconnect.com
The function of the Toll-like receptor (TLR) family members has been extensively studied in
the recent decades. The TLR family is generally involved in the defense against microbial …

Toll‐like receptors: A pathway alluding to cancer control

AP Ayala‐Cuellar, J Cho… - Journal of cellular …, 2019 - Wiley Online Library
Toll‐like receptors (TLRs) are usually expressed on immune cells such as macrophages,
dendritic cells, mast cells, as well as on eosinophils and some epithelial cells. They play a …

Toll-like receptors expressed in tumor cells: targets for therapy

L Yu, S Chen - Cancer Immunology, Immunotherapy, 2008 - Springer
Abstract Toll-like receptors (TLRs), mainly expressing in human immune related cells and
epithelial cells, play an essential role in the host defense against microbes by recognizing …

Application potential of toll-like receptors in cancer immunotherapy: Systematic review

M Shi, X Chen, K Ye, Y Yao, Y Li - Medicine, 2016 - journals.lww.com
Abstract Toll-like receptors (TLRs), as the most important pattern recognition receptors in
innate immunity, play a pivotal role in inducing immune response through recognition of …

Toll‐like receptors (TLRs) in cancer; with an extensive focus on TLR agonists and antagonists

A Keshavarz, A Pourbagheri‐Sigaroodi, P Zafari… - IUBMB …, 2021 - Wiley Online Library
At the forefront of the battle against pathogens or any endogenously released molecules, toll‐
like receptors (TLRs) play an important role as the most noble pattern recognition receptors …

Toll-like receptors (TLRs): the role in tumor progression

DV Shchebliakov, DY Logunov… - Acta Naturae …, 2010 - cyberleninka.ru
Toll-like receptors (TLRs) are major components of the innate immune system that recognize
the conserved molecular structures of pathogens (pathogen-associated molecular patterns; …