Transcriptome profiles of organ tissues from pigs experimentally infected with African swine fever virus in early phase of infection

SI Oh, S Sheet, VN Bui, DT Dao, NA Bui… - Emerging Microbes & …, 2024 - Taylor & Francis
African swine fever, caused by African swine fever virus (ASFV), is a highly contagious and
fatal disease that poses a significant threat to the global pig industry. The limited information …

Transcriptome profiling reveals features of immune response and metabolism of acutely infected, dead and asymptomatic infection of African swine fever virus in pigs

H Sun, Q Niu, J Yang, Y Zhao, Z Tian, J Fan… - Frontiers in …, 2021 - frontiersin.org
African swine fever virus (ASFV) infection can result in lethal disease in pigs. ASFV encodes
150-167 proteins, of which only approximately 50 encoded viral structure proteins are …

Transcriptome profiling in swine macrophages infected with African swine fever virus at single-cell resolution

Y Zheng, S Li, SH Li, S Yu, Q Wang… - Proceedings of the …, 2022 - National Acad Sciences
African swine fever virus (ASFV) is the causative agent of African swine fever, a highly
contagious and usually fatal disease in pigs. The pathogenesis of ASFV infection has not …

Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics

L Lv, T Zhang, H Jia, Y Zhang, A Ahsan… - Frontiers in …, 2022 - frontiersin.org
African swine fever virus (ASFV) causes a lethal swine hemorrhagic disease and is currently
responsible for widespread damage to the pig industry. The pathogenesis of ASFV infection …

Single-cell profiling of African swine fever virus disease in the pig spleen reveals viral and host dynamics

Z Zhu, R Mao, B Liu, H Liu, Z Shi… - Proceedings of the …, 2024 - National Acad Sciences
African swine fever, one of the major viral diseases of swine, poses an imminent threat to the
global pig industry. The high-efficient replication of the causative agent African swine fever …

Transcriptome profiling in swine macrophages infected with African Swine Fever Virus (ASFV) uncovers the complex and close relationship with host

Z Li, W Chen, X Li, K Wu, X Wang, W Wang, Y Li, L Yi… - Pathogens, 2022 - mdpi.com
African swine fever virus (ASFV) is a pathogen to cause devastating and economically
significant diseases in domestic and feral swine. ASFV mainly infects macrophages and …

Infection characteristics and transcriptomics of African swine fever virus in Bama minipigs

C Lv, J Yang, L Zhao, C Wu, C Kang… - Microbiology …, 2022 - Am Soc Microbiol
Animal experiments on African swine fever virus (ASFV) are vital to the study of ASFV;
however, ASFV can only infect pigs, and animal experiments need to be performed in …

Genome-wide transcriptomic analysis of highly virulent African swine fever virus infection reveals complex and unique virus host interaction

X Ju, F Li, J Li, C Wu, G Xiang, X Zhao, Y Nan… - Veterinary …, 2021 - Elsevier
African swine fever virus (ASFV), one of the most devastating emerging swine pathogens in
China, causes nearly 100% mortality in naive herds. Here, whole-transcriptome RNA-seq …

Gene expression analysis of whole blood RNA from pigs infected with low and high pathogenic African swine fever viruses

C Jaing, RRR Rowland, JE Allen, A Certoma… - Scientific reports, 2017 - nature.com
African swine fever virus (ASFV) is a macrophage-tropic virus responsible for ASF, a
transboundary disease that threatens swine production world-wide. Since there are no …

Transcriptomic analysis reveals upregulated host metabolisms and downregulated immune responses or cell death induced by acute African swine fever virus …

S Cao, P Jia, Z Wu, H Lu, Y Cheng, C Chen… - Frontiers in Veterinary …, 2023 - frontiersin.org
The African swine fever virus is a virulent and communicable viral disease that can be
transmitted by infected swine, contaminated pork products, or soft tick vectors. Nonstructural …