The next wave of asthma genetic studies will use full-genome sequencing and overcome
most GWAS-associated problems. It will be the last step of a century-long search for asthma …

Moving beyond traditional GWAS formats is likely to significantly enhance our understanding
of the genetic basis for asthma. This review discusses where we are after half a decade of …

Asthma is a common complex disease of the airways. Genome-wide association studies
(GWASs) of asthma have identified many risk alleles and loci that have been replicated in …

In the era of genome-wide association (GWA) studies, delineating pathogenic asthma
genetic pathways has provided both challenges and opportunities. Initial GWA studies on …

Asthma is a complex disease determined by the interaction of different genes and
environmental factors. The first genetic investigations in asthma were candidate gene …

Asthma is a complex syndrome leading to the easily recognizable clinical feature of
wheezing. This is believed to be caused by inflammation, constriction of the airway smooth …

Genome-wide association studies (GWAS) of asthma have yielded exciting results and
identified novel risk alleles and loci. But, like other common complex diseases, asthma …

The field of asthma genetics has progressed rapidly over the past decade, implicating many
genes and variants in the etiology of this complex disease. However, many of these factors …

Asthma is the result of a complex interaction between environmental factors and genetic
variants that confer susceptibility. Studies of the genetics of asthma have previously been …

Asthma genes have been identified through a range of approaches, from candidate gene
association studies and family-based genome-wide linkage analyses to genome-wide …