Salt and fluid absorption and secretion are two processes that are fundamental to epithelial
function and whole body fluid homeostasis, and as such are tightly regulated in epithelial …

The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-regulated
chloride channel located primarily at the apical or luminal surfaces of epithelial cells in the …

Cystic fibrosis (CF) is a recessive genetic disease caused by mutations in a gene encoding
a protein called Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). The CFTR …

Epithelial salt and water secretion serves a variety of functions in different organ systems,
such as the airways, intestines, pancreas, and salivary glands. In cystic fibrosis (CF), the …

Cystic fibrosis is a hereditary disease that mainly affects secretory organs in humans. It is
caused by mutations in the gene encoding CFTR with the most common phenylalanine …

Cystic fibrosis, a multi-organ genetic disease, is characterized by abnormal function of the
cystic fibrosis transmembrane conductance regulator (CFTR) protein, a chloride channel at …

Cystic fibrosis (CF) transmembrane conductance regulator (CFTR) chloride channel plays a
critical role in regulating transepithelial movement of water and electrolyte in exocrine …

Mutations in the gene coding for the cystic fibrosis transmembrane conductance regulator
(CFTR) epithelial anion channel cause cystic fibrosis (CF). The multidomain integral …

CFTR is a cAMP-activated chloride and bicarbonate channel that is critical for lung
homeostasis. Decreases in CFTR expression have dire consequences in cystic fibrosis (CF) …

Cystic fibrosis (CF) is a fatal genetic disease primarily affecting Caucasians, although cases
have been reported from other ethnic groups. CF has a complex etiology, but it is chiefly a …