Salix babylonica L. mitigates pancreatic damage by regulating the Beclin-P62/SQSTM1 autophagy pathway in rats

MF Mahmoud, N Tawfeek, N Ali, RA Hasan… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Salix babylonica L. belongs to the genus Salix, family
Salicaceae. It is traditionally used as an antipyretic, antirheumatic, antidiabetic and for the …

The root extract of Scutellaria baicalensis Georgi promotes β cell function and protects from apoptosis by inducing autophagy

J Zhou, Y Luo, X Kang, F Bian, D Liu - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Scutellaria baicalensis Georgi (SBG) is a traditional
Chinese medicine with a remarkable remedial effect on diabetes mellitus. However, the …

Protective effects of baicalin on caerulein-induced AR42J pancreatic acinar cells by attenuating oxidative stress through miR-136-5p downregulation

Z Zhao, Y Zhang, Y Sun, C Zhang, M Liu - Science Progress, 2021 - journals.sagepub.com
Baicalin, the main active component of Scutellaria baicalensis, has antioxidant and anti-
apoptotic effects and is used to treat acute pancreatitis; however, its specific mechanism is …

Protective effect of salvianolic acid B on pancreatic islet cells in diabetic rats with fluctuating blood glucose

SJ TAO - Chinese Traditional and Herbal Drugs, 2016 - pesquisa.bvsalud.org
Objective: To observe the protective effect of salvianolic acid B (Sal B) on pancreatic islet
cells in diabetic rats with fluctuating blood glucose and the possible mechanisms implicated …

Saikosaponin d ameliorates pancreatic fibrosis by inhibiting autophagy of pancreatic stellate cells via PI3K/Akt/mTOR pathway

LH Cui, CX Li, YZ Zhuo, L Yang, NQ Cui… - Chemico-biological …, 2019 - Elsevier
Chronic pancreatitis is characterized by pancreatic fibrosis, associated with excessive
activation of pancreatic stellate cells (PSCs) and increased expression of transforming …

Ameliorative potential of Lavandula stoechas in metabolic syndrome via multitarget interactions

SS Kulabas, H Ipek, AR Tufekci, S Arslan… - Journal of …, 2018 - Elsevier
Ethnopharmacological importance Decoction and infusion prepared from aerial parts of
Lavandula stoechas L.(L. stoechas) have been traditionally used as remedy against several …

Baicalein attenuates pancreatic inflammatory injury through regulating MAPK, STAT 3 and NF-κB activation

WL Pu, RY Bai, K Zhou, YF Peng, MY Zhang… - International …, 2019 - Elsevier
Acute pancreatitis (AP) is a common acute abdominal disease with local or systemic
inflammatory response, caused by abnormal activation of digestive enzymes. Baicalein has …

[HTML][HTML] Flavonoids identification and pancreatic beta-cell protective effect of lotus seedpod

MS Lee, CC Chyau, CP Wang, TH Wang, JH Chen… - Antioxidants, 2020 - mdpi.com
Oxidative stress is highly associated with the development of diabetes mellitus (DM),
especially pancreatic beta-cell injury. Flavonoids derived from plants have caused important …

[HTML][HTML] Saikosaponin D attenuates pancreatic injury through suppressing the apoptosis of acinar cell via modulation of the MAPK signaling pathway

C Li, L Cui, L Zhang, L Yang, Y Zhuo, J Cui… - Frontiers in …, 2021 - frontiersin.org
Chronic pancreatitis (CP) is a progressive fibro-inflammatory syndrome. The damage of
acinar cells is the main cause of inflammation and the activation of pancreatic stellate cells …

Launaea acanthodes (Boiss) O. Kuntze mediates hepatic glucose metabolism and ameliorates impaired pancreatic function in streptozotocin-induced diabetic rats

M Marvibaigi, SM Hosseini, N Amini - Journal of Ethnopharmacology, 2021 - Elsevier
Abstract Ethnopharmacological relevance Launaea acanthodes (Boiss.) O. Kuntze is native
to semiarid regions of central Iran, traditionally used in the treatment of numerous disorders …