The effect of free fatty acids on rat brain particulate hexokinase was studied in vitro.
Hexokinase bound with brain mitochondrial fraction was found to be sensitive to the action …

Abstract——‐(1) The total hexokinase activity present in the mitochondrial fraction can be
solubilized completely by incubation with salt and Triton X‐100. This activity cannot be …

The distribution of protein and of the marker enzymes, cytochrome oxidase, lactate
dehydrogenase, and acetylcholinesterase, among the fractions is shown in Fig. 2. Even …

In Brain tissue only 10–20 percent of the total hexokinase activity (EC 2.7. 1.1) is present in
the cytoplasm whereas the particulate activity is associated with mitochondria (Bachelard …

The intracellular location of brain hexokinase and the nature of its association with
mitochondria were studied in calf and rat. Three different media were used in order to …

The distribution of hexokinase, inactivated and activated by Triton X-100, in subcellular
fractions of the rat cortex was investigated. Latent hexokinase, inactivated and activated by …

Cytoplasmic hexokinase (ATP: d‐hexose 6‐phosphotransferase, EC 2.7. 1.1) was purified
from the soluble fraction of a rat brain homogenate by a procedure that included a unique …

1. Cerebral-cortex mitochondria, after purification by using high-density sucrose solutions,
were extracted with Triton X-100. The total hexokinase activity of the intact mitochondria was …

The previous suggestion I for the involvement of the soluble-particulate distribution in
regulating brain hexokinase (ATP: D-hexose 6-phosphotransferase, EC 2.7. i. 1) activity may …

Initial rate kinetic studies of soluble rat brain hexokinase indicate that the kinetic mechanism
is random Bi Bi. These studies also indicate that the ADP interaction with enzyme cannot be …