Network pharmacology, molecular docking-driven, Qbd-Engineered antifungal in-situ gel loaded with voriconazole nanostructured lipid carriers
Fungal infections (FIs) affect majority of the population, but the current treatments face
challenges in terms of their effectiveness. This study focused on specific fungal targets …
challenges in terms of their effectiveness. This study focused on specific fungal targets …
Voriconazole loaded nanostructured lipid carriers based topical delivery system: QbD based designing, characterization, in-vitro and ex-vivo evaluation
T Waghule, VK Rapalli, G Singhvi, P Manchanda… - Journal of drug delivery …, 2019 - Elsevier
Clinical investigation showed that voriconazole exhibits various adverse effects such as
nausea, vomiting, and other gastric disturbances. To overcome these associated side …
nausea, vomiting, and other gastric disturbances. To overcome these associated side …
Development and optimization of luliconazole nanostructured lipid carriers based gel by quality by design its skin distribution studies, dermatokinetic modeling & in …
E Bhargav, YP Reddy, KB Koteshwara - Current Drug Delivery, 2021 - ingentaconnect.com
Aim: The present study was aimed to improve the permeability of Luliconazole (LZ) and to
localize high drug concentrations at skin layers by Quality by Design (QbD) based …
localize high drug concentrations at skin layers by Quality by Design (QbD) based …
QbD-Driven Development and Characterization of Solid Lipid Nanoparticles (SLNs)–Based Nanogel of Luliconazole for the Effective Management of Dermal Fungal …
G Khurana, VV Sharma, D Arora - Journal of Pharmaceutical Innovation, 2023 - Springer
Abstract Purpose Solid lipid nanoparticles (SLNs) have shown tremendous utility in the
topical delivery of such anti-fungal moieties. Hence, it was aimed to develop luliconazole …
topical delivery of such anti-fungal moieties. Hence, it was aimed to develop luliconazole …
Formulation and molecular docking simulation study of luliconazole nanosuspension–based nanogel for transdermal drug delivery using modified polymer
MS Shaikh, MA Kale - Materials Today Chemistry, 2020 - Elsevier
The purpose of study was to formulate nanosuspension-based nanogel of luliconazole (LLZ)
for transdermal delivery to enhance its skin retention and effectiveness using modified starch …
for transdermal delivery to enhance its skin retention and effectiveness using modified starch …
Enhanced antifungal activity of voriconazole-loaded nanostructured lipid carriers against Candida albicans with a dimorphic switching model
B Tian, Q Yan, J Wang, C Ding, S Sai - International Journal of …, 2017 - Taylor & Francis
Candida commonly adheres to implanted medical devices and forms biofilms. Due to the
minimal activity of current antifungals against biofilms, new drugs or drug-delivery systems to …
minimal activity of current antifungals against biofilms, new drugs or drug-delivery systems to …
Dermatokinetic assessment of luliconazole-loaded nanostructured lipid carriers (NLCs) for topical delivery: QbD-driven design, optimization, and in vitro and ex vivo …
A Mahmood, VK Rapalli, S Gorantla, T Waghule… - Drug Delivery and …, 2022 - Springer
The present study is concerned with the QbD-based design and development of
luliconazole-loaded nanostructured lipid carriers (NLCs) hydrogel for enhanced skin …
luliconazole-loaded nanostructured lipid carriers (NLCs) hydrogel for enhanced skin …
Limonene-Enriched Ultra-Structural Cubosomes to Augment Ocular Delivery of a Poorly Water Soluble Anti-Fungal Drug: Fabrication, Characterization, Statistical …
The target of this investigation was to obtain the composition of the optimized Fenticonazole
nitrate (FCN)-loaded cubosomal formula that can prolong precorneal retention, increase …
nitrate (FCN)-loaded cubosomal formula that can prolong precorneal retention, increase …
Luliconazole loaded lyotropic liquid crystalline nanoparticles for topical delivery: QbD driven optimization, in-vitro characterization and dermatokinetic assessment
A Mahmood, VK Rapalli, T Waghule, S Gorantla… - Chemistry and physics …, 2021 - Elsevier
Fungal infections are an important cause of morbidity and pose a serious health concern
especially in immunocompromised patients. Luliconazole (LUL) is a topical imidazole …
especially in immunocompromised patients. Luliconazole (LUL) is a topical imidazole …
[PDF][PDF] Design and assessment of in silico screened diosmin incorporated ultra-flexible topical lipid gel system for the treatment of varicose vein
The ultra-flexible lipid gel system (UFLGS) consists of bilayer lipid membranes, responsible
for highly elastic and deformable vesicles compared to conventional topical systems …
for highly elastic and deformable vesicles compared to conventional topical systems …