Abstract Background and Aims Despite relevance to pain chronicity, disease burden, and
treatment, mechanisms of pain perception for different types of acute pain remain …

Abdominal pain is a common symptom of inflammatory bowel disease (IBD: Crohn's
disease, ulcerative colitis). Pain may arise from different mechanisms, which can include …

Background Typically, conventional functional imaging methods involve repeated exposures
to sensory stimulation. In rectal distension (RD) studies that involve multiple distensions …

Irritable bowel syndrome (IBS) is a highly prevalent gastrointestinal disorder that is often
accompanied by both visceral and somatic hyperalgesia (enhanced pain from colorectal …

Patients with inflammatory bowel disease often experience ongoing pain even after
achieving mucosal healing (ie, post-inflammatory pain). Factors related to the brain–gut axis …

Background A subset of ulcerative colitis (UC) patients in remission demonstrate IBS‐like
symptoms. Visceral hypersensitivity is a key pathophysiological mechanism in IBS, but its …

Chronic abdominal pain is a common symptom of great clinical significance in several areas
of medicine. In many cases no organic cause can be established resulting in the …

Abdominal pain in patients with inflammatory bowel diseases (IBDs) is very common and up
to 80% of patients experience some type of acute pain as a result of inflammation and/or …

Recent reports have emphasized the possible role of mucosal immune activation and
inflammation in neuropathic changes in the pathophysiology of irritable bowel syndrome …

Objective To address the role of anxiety and depression symptoms in altered pain
processing in irritable bowel syndrome (IBS). Design In this functional magnetic resonance …