Screening with MRI for accurate and rapid stroke treatment: SMART

S Shah, M Luby, K Poole, T Morella, E Keller… - Neurology, 2015 - AAN Enterprises
Objective: The objective of this study was to demonstrate the feasibility of timely multimodal
MRI screening before thrombolysis in acute stroke patients. Methods: Quality improvement …

Target door-to-needle time for tissue plasminogen activator treatment with magnetic resonance imaging screening can be reduced to 45 min

D Sablot, I Ion, K Khlifa, G Farouil, F Leibinger… - Cerebrovascular …, 2018 - karger.com
Objective: The purpose of this study was to demonstrate that the median door-to-needle
(DTN) time for intravenous tissue plasminogen activator (tPA) treatment can be reduced to …

Comparison between MRI screening and CT-plus-MRI screening for thrombolysis within 3 h of ischemic stroke

SH Yoo, SU Kwon, DH Lee, SJ Kim, JS Kim… - Journal of the …, 2010 - Elsevier
BACKGROUND AND PURPOSE: Although MRI may provide much information on brain
pathology to aid in patient selection for thrombolysis, the concern remains that MRI …

MRI screening before standard tissue plasminogen activator therapy is feasible and safe

DW Kang, JA Chalela, W Dunn, S Warach… - Stroke, 2005 - Am Heart Assoc
Background and Purpose—MRI screening for thrombolytic therapy may improve patient
selection. Alternatively, it may excessively delay treatment and thereby lead to worse …

Multimodal CT or MRI for IV thrombolysis in ischemic stroke with unknown time of onset

K Macha, P Hoelter, G Siedler, M Knott, S Schwab… - Neurology, 2020 - AAN Enterprises
Objective To investigate differences in procedure times, safety, and efficacy outcomes
comparing 2 different protocols to enable thrombolysis in the extended or unknown time …

Feasibility and logistics of MRI before thrombolytic treatment

C Sølling, M Ashkanian, N Hjort… - Acta neurologica …, 2009 - Wiley Online Library
Objectives–The study analyzes feasibility and time‐delays in Magnetic resonance imaging
(MRI) based thrombolysis and estimate the impact of MRI on individual tissue plasminogen …

tPA for stroke: important progress in achieving faster treatment

JC Grotta - Jama, 2014 - jamanetwork.com
Intravenous tissue plasminogen activator (tPA) remains the only level 1A treatment for acute
ischemic stroke. The results of several prospective randomized trials comparing tPA with …

Tissue window, not the time window, will guide acute stroke treatment

D Wang, Y Wang - Stroke and Vascular Neurology, 2019 - svn.bmj.com
Since the approval of intravenous (IV) tissue plasminogen activator (tPA) to treat patients
with acute ischaemic stroke (AIS) within 3 hours of onset in 1996, it took 12 years to expand …

Critical care and emergency medicine neurology in stroke

D Hanley, W Hacke - Stroke, 2005 - Am Heart Assoc
acute ischemic stroke treatment. The most important event was the publication of the meta-
analysis of the recent large stroke trials, including NINDS, ECASS, and ATLANTIS. 20 This …

A mobile stroke treatment unit for field triage of patients for intraarterial revascularization therapy

R Cerejo, S John, AB Buletko, A Taqui… - Journal of …, 2015 - Wiley Online Library
ABSTRACT INTRODUCTION Favorable outcomes in intraarterial therapy (IAT) for acute
ischemic stroke (AIS) are related to early vessel recanalization. The mobile stroke treatment …