Inflammation can arise in response to a variety of stimuli, including infectious agents, tissue
injury, autoimmune diseases, and obesity. Some of these responses are acute and resolve …

Abstract Purpose of Review Metabolic syndrome (MetS), also called the 'deadly
quartet'comprising obesity, diabetes, dyslipidemia, and hypertension, has been ascertained …

Metabolic osteoarthritis (OA) has now been characterized as a subtype of OA, and links
have been discovered between this phenotype and metabolic syndrome (MetS)—both with …

Sarcopenic obesity is becoming a global health concern, owing to the rising older
population, causing cardiometabolic morbidity and mortality. Loss of muscle exceeding …

Obesity and associated metabolic diseases collectively referred to as the metabolic
syndrome increase the risk of skeletal and synovial joint diseases, including osteoarthritis …

Skeletal muscle constitutes the largest insulin‐sensitive tissue in the body and is the primary
site for insulin‐stimulated glucose utilization. Skeletal muscle resistance to insulin is …

Obesity has a significant impact on the musculoskeletal system being associated with both
degenerative and inflammatory conditions. Future research assessing the effects of obesity …

Obesity is associated with chronic inflammation, which contributes to insulin resistance and
type 2 diabetes mellitus. Under normal conditions, skeletal muscle is responsible for the …

Osteoarthritis (OA) is a heterogeneous disorder with several risk factors. Among them,
obesity has a major impact on both loading and non-loading joints. Mechanical overload …

Skeletal muscles contain resident immune cell populations and their abundance and type is
altered in inflammatory myopathies, endotoxemia or different types of muscle injury/insult …