In the pediatric population, B-acute lymphoblastic leukemia (B-ALL) is the most prevalent
childhood hematological malignancy, as well as the leading cause of childhood cancer …

Acute lymphoblastic leukemia (ALL), the most common malignancy of childhood, is a
genetically complex entity that remains a major cause of childhood cancer‐related mortality …

Childhood acute lymphoblastic leukemia (ALL) is comprised of multiple subtypes defined by
recurring chromosomal alterations that are important events in leukemogenesis and are …

The last decade has witnessed great advances in our understanding of the genetic and
biological basis of childhood acute lymphoblastic leukemia (ALL), the development of …

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and despite cure
rates exceeding 90% in children, it remains an important cause of morbidity and mortality in …

Advances in genomic research and risk-directed therapy have led to improvements in the
long-term survival and quality of life outcomes of patients with childhood acute lymphoblastic …

Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and a
leading case of childhood cancer death. The last decade has witnessed a transformation in …

To resolve the genetic heterogeneity within pediatric high-risk B-precursor acute
lymphoblastic leukemia (ALL), a clinically defined poor-risk group with few known recurring …

We sequenced 120 candidate genes in 187 high-risk childhood B-precursor acute
lymphoblastic leukemias, the largest pediatric cancer genome sequencing effort reported to …

A key goal in cancer research is to identify the total complement of genetic and epigenetic
alterations that contribute to tumorogenesis. We are currently witnessing the rapid evolution …