Corynebacterium pseudotuberculosis fosfolipaz d (PLD) geninin aktarımı ve PLD enziminin aşı olarak kullanılması

A Sakmanoğlu - 2015 - acikerisim.selcuk.edu.tr
Özet Özellikle koyun ve keçilerde Kazeöz Lenfadenitise (KLA) sebep olan Corynebacterium
pseudotuberculosis, patojenitesinde önemli rol oynayan fosfolipaz D (PLD) ekzotoksinini …

Farelerde ve koyunlarda inaktif Corynebacterium pseudotuberculosis aşısının kazeöz lenfadenitise karşı etkinliği

O Erganiş, HH Hadimli, K Kav, A Sakmanoğlu, Z Sayın… - 2014 - acikerisim.selcuk.edu.tr
Amaç: Bu çalışmada, Kazeöz Lenfadenitis'e (KLA) karşı hazırlanan Corynebacterium
pseudotuberculosis aşısının etkinliğini fare ve koyunlarda belirlemek amaçlandı. Gereç ve …

Protection of sheep against caseous lymphadenitis by use of a single oral dose of live recombinant Corynebacterium pseudotuberculosis

AL Hodgson, M Tachedjian, LA Corner… - Infection and …, 1994 - Am Soc Microbiol
An inactive form of the Corynebacterium pseudotuberculosis phospholipase D (PLD) gene
was constructed and expressed in a PLD-negative strain (designated Toxminus) of C …

[HTML][HTML] A novel approach for an immunogen against Corynebacterium pseudotuberculosis infection: An Escherichia coli bacterin expressing phospholipase D

RB de Pinho, MT de Oliveira Silva, G Brenner… - Microbial …, 2021 - Elsevier
Corynebacterium pseudotuberculosis is the causative agent of caseous lymphadenitis
(CLA) in small ruminants. There is still needed an immunoprophylaxis model, which induces …

[PDF][PDF] Koyunlardan izole edilen Corynebacterium pseudotuberculosis suşlarının identifikasyonu ve antibiyotiklere duyarlılıkları

A Sakmanoğlu, HH Hadimli, O Erganiş… - Eurasian J Vet …, 2015 - eurasianjvetsci.org
Öz Amaç: Bu çalışmada, Kazeöz Lenfadenetis (KLA)'li koyunların lenf dü-ğümlerinden izole
edilen Corynebacterium pseudotuberculosis (C. pseudotuberculosis) izolatlarının …

[PDF][PDF] Comparison of protection against caseous lymphadenitis in sheep induced by local isolated strain of corynebacterium pseudotuberculosis by toxoid pld & toxoid …

MS Sohier, S Selim, M Bakry, E Elgabry… - Int. J. Dev …, 2017 - researchgate.net
Background: The objective of the present study was directed to perform a comparative study
for the protective efficacy of different vaccine formulation to evoke protection against …

Association of Corynebacterium pseudotuberculosis recombinant proteins rCP09720 or rCP01850 with rPLD as immunogens in caseous lymphadenitis …

MT de Oliveira Silva, FSB Bezerra, RB de Pinho… - Vaccine, 2018 - Elsevier
Caseous lymphadenitis (CLA) is a chronic disease responsible for significant economic
losses in sheep and goat breeding worldwide. The treatment for this disease is not effective …

Rational attenuation of Corynebacterium pseudotuberculosis: potential cheesy gland vaccine and live delivery vehicle

AL Hodgson, J Krywult, LA Corner, JS Rothel… - Infection and …, 1992 - Am Soc Microbiol
The phospholipase D (PLD) gene (pld) has been deleted from the Corynebacterium
pseudotuberculosis chromosome by using site-specific mutagenesis. Sheep infection trials …

[PDF][PDF] Studies on vaccine development for ovine caseous lymphadenitis

M İzgür, M Akan, Z Ilhan, N Yazıcıoğlu - … Veteriner Fakültesi Dergisi, 2010 - dergipark.org.tr
Caseous lymphadenitis (CLA), which is a serious infectious disease of sheep and goats
world-wide, has caused significant economic losses in Turkey in recent years. In this study, it …

[HTML][HTML] Distribution of PLD and FagA, B, C and D genes in Corynebacterium pseudotuberculosis isolates from sheep and goats with caseus lymphadenitis

MCA Sá, GV Gouveia, CC Krewer… - … and Molecular Biology, 2013 - SciELO Brasil
Caseous lymphadenits (CL) is a chronic and subclinical disease that affects goats and
sheep and, consequently, causes economic losses, especially to small producers. The …