Association of body-shape phenotypes with imaging measures of body composition in the UK Biobank cohort: relevance to colon cancer risk

S Christakoudi, KK Tsilidis, E Evangelou, E Riboli - BMC cancer, 2021 - Springer
Background Body mass index (BMI), waist and hip circumference are strongly correlated
and do not reflect body composition. A Body Shape Index (ABSI) and Hip Index (HI) define …

Allometric versus traditional body-shape indices and risk of colorectal cancer: a Mendelian randomization analysis

MO Rontogianni, E Bouras, EK Aglago… - International Journal of …, 2024 - nature.com
Background Traditional body-shape indices such as Waist Circumference (WC), Hip
Circumference (HC), and Waist-to-Hip Ratio (WHR) are associated with colorectal cancer …

A prospective investigation of body size, body fat composition and colorectal cancer risk in the UK Biobank

LS Ortega, KE Bradbury, AJ Cross, JS Morris… - Scientific reports, 2017 - nature.com
Obesity has been consistently associated with a greater colorectal cancer risk, but this
relationship is weaker among women. In the UK Biobank, we investigated the associations …

Tissue-specific genetic variation suggests distinct molecular pathways between body shape phenotypes and colorectal cancer

L Peruchet-Noray, AM Sedlmeier, N Dimou… - Science …, 2024 - science.org
It remains unknown whether adiposity subtypes are differentially associated with colorectal
cancer (CRC). To move beyond single-trait anthropometric indicators, we derived four multi …

A nested case–control study of metabolically defined body size phenotypes and risk of colorectal cancer in the European Prospective Investigation into Cancer and …

N Murphy, AJ Cross, M Abubakar, M Jenab… - PLoS …, 2016 - journals.plos.org
Background Obesity is positively associated with colorectal cancer. Recently, body size
subtypes categorised by the prevalence of hyperinsulinaemia have been defined, and …

Body size and composition and risk of site-specific cancers in the UK Biobank and large international consortia: A mendelian randomisation study

M Vithayathil, P Carter, S Kar, AM Mason… - PLoS …, 2021 - journals.plos.org
Background Evidence for the impact of body size and composition on cancer risk is limited.
This mendelian randomisation (MR) study investigates evidence supporting causal …

A Body Shape Index (ABSI), hip index, and risk of cancer in the UK Biobank cohort

S Christakoudi, KK Tsilidis, E Evangelou… - Cancer …, 2021 - Wiley Online Library
Abdominal size is associated positively with the risk of some cancers but the influence of
body mass index (BMI) and gluteofemoral size is unclear because waist and hip …

Body shape phenotypes of multiple anthropometric traits and cancer risk: a multi-national cohort study

AM Sedlmeier, V Viallon, P Ferrari… - British Journal of …, 2023 - nature.com
Background Classical anthropometric traits may fail to fully represent the relationship of
weight, adiposity, and height with cancer risk. We investigated the associations of body …

Associations of A Body Shape Index (ABSI) with Cancer Incidence, All-Cause, and at 23 Sites—Findings from the UK Biobank Prospective Cohort Study

S Parra-Soto, FC Malcomson, FK Ho, JP Pell… - … Biomarkers & Prevention, 2022 - AACR
Background: Few studies have explored the emerging adiposity marker A Body Shape Index
(ABSI) with cancer risk. This study investigated the associations between ABSI and the …

Self-reported and measured anthropometric data and risk of colorectal cancer in the EPIC–Norfolk study

JY Park, PN Mitrou, RH Keogh, RN Luben… - International journal of …, 2012 - nature.com
Background: Epidemiological studies have shown inconsistent results for the association
between body size and colorectal cancer (CRC) risk. Inconsistencies may be because of the …