Vaporized E-cigarette liquids induce ion transport dysfunction in airway epithelia
VY Lin, MD Fain, PL Jackson, TF Berryhill… - American journal of …, 2019 - atsjournals.org
Cigarette smoking is associated with chronic obstructive pulmonary disease and chronic
bronchitis. Acquired ion transport abnormalities, including cystic fibrosis transmembrane …
bronchitis. Acquired ion transport abnormalities, including cystic fibrosis transmembrane …
Airway epithelial cell exposure to distinct e-cigarette liquid flavorings reveals toxicity thresholds and activation of CFTR by the chocolate flavoring 2, 5-dimethypyrazine
CL Sherwood, S Boitano - Respiratory research, 2016 - Springer
Background The potential for adverse respiratory effects following exposure to electronic (e-)
cigarette liquid (e-liquid) flavorings remains largely unexplored. Given the multitude of flavor …
cigarette liquid (e-liquid) flavorings remains largely unexplored. Given the multitude of flavor …
Inhibition of chloride secretion in human bronchial epithelial cells by cigarette smoke extract
JL Kreindler, AD Jackson, PA Kemp… - … of physiology-lung …, 2005 - journals.physiology.org
Chronic bronchitis, a disease mainly of cigarette smokers, shares many clinical features with
cystic fibrosis, a disease of altered ion transport, suggesting that the negative effects of …
cystic fibrosis, a disease of altered ion transport, suggesting that the negative effects of …
Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice
LE Crotty Alexander, CA Drummond… - American Journal …, 2018 - journals.physiology.org
Electronic (e)-cigarettes theoretically may be safer than conventional tobacco. However, our
prior studies demonstrated direct adverse effects of e-cigarette vapor (EV) on airway cells …
prior studies demonstrated direct adverse effects of e-cigarette vapor (EV) on airway cells …
Cigarette and ENDS preparations differentially regulate ion channels and mucociliary clearance in primary normal human bronchial 3D cultures
Cigarette smoking is known to disrupt the normal mucociliary function of the lungs, whereas
the effect of electronic nicotine delivery systems (ENDS) is not completely understood. This …
the effect of electronic nicotine delivery systems (ENDS) is not completely understood. This …
Cigarette smoke-induced Ca2+ release leads to cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction
JE Rasmussen, JT Sheridan, W Polk, CM Davies… - Journal of Biological …, 2014 - ASBMB
Chronic obstructive pulmonary disease affects 64 million people and is currently the fourth
leading cause of death worldwide. Chronic obstructive pulmonary disease includes both …
leading cause of death worldwide. Chronic obstructive pulmonary disease includes both …
Flavored e-cigarette liquids reduce proliferation and viability in the CALU3 airway epithelial cell line
TR Rowell, SL Reeber, SL Lee… - … of Physiology-Lung …, 2017 - journals.physiology.org
E-cigarettes are generally thought of as a safer smoking alternative to traditional cigarettes.
However, little is known about the effects of e-cigarette liquids (e-liquids) on the lung. Since …
However, little is known about the effects of e-cigarette liquids (e-liquids) on the lung. Since …
Cigarette smoke induces systemic defects in cystic fibrosis transmembrane conductance regulator function
SV Raju, PL Jackson, CA Courville… - American journal of …, 2013 - atsjournals.org
Rationale: Several extrapulmonary disorders have been linked to cigarette smoking.
Smoking is reported to cause cystic fibrosis transmembrane conductance regulator (CFTR) …
Smoking is reported to cause cystic fibrosis transmembrane conductance regulator (CFTR) …
[HTML][HTML] Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration
LA Clunes, CM Davies, RD Coakley… - The FASEB …, 2012 - ncbi.nlm.nih.gov
Cigarette smoke (CS) exposure induces mucus obstruction and the development of chronic
bronchitis (CB). While many of these responses are determined genetically, little is known …
bronchitis (CB). While many of these responses are determined genetically, little is known …
Sub-ohm vaping increases the levels of carbonyls, is cytotoxic, and alters gene expression in human bronchial epithelial cells exposed at the air–liquid interface
Background Exposure to electronic-cigarette (e-cig) aerosols induces potentially fatal e-cig
or vaping-associated lung injury (EVALI). The cellular and molecular mechanisms …
or vaping-associated lung injury (EVALI). The cellular and molecular mechanisms …