Environmental chemical exposures and human epigenetics

L Hou, X Zhang, D Wang… - International journal of …, 2012 - academic.oup.com
Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

Epigenetic epidemiology: promises for public health research

KM Bakulski, MD Fallin - Environmental and molecular …, 2014 - Wiley Online Library
Epigenetic changes underlie developmental and age related biology. Promising
epidemiologic research implicates epigenetics in disease risk and progression, and …

The promises and challenges of toxico-epigenomics: environmental chemicals and their impacts on the epigenome

FFL Chung, Z Herceg - Environmental Health Perspectives, 2020 - ehp.niehs.nih.gov
Background: It has been estimated that a substantial portion of chronic and
noncommunicable diseases can be caused or exacerbated by exposure to environmental …

Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships

VK Cortessis, DC Thomas, AJ Levine, CV Breton… - Human genetics, 2012 - Springer
Abstract Changes in epigenetic marks such as DNA methylation and histone acetylation are
associated with a broad range of disease traits, including cancer, asthma, metabolic …

The role of environmental exposures and the epigenome in health and disease

BPU Perera, C Faulk, LK Svoboda… - Environmental and …, 2020 - Wiley Online Library
The genetic material of every organism exists within the context of regulatory networks that
govern gene expression, collectively called the epigenome. Epigenetics has taken center …

Environmental epigenetics

V Bollati, A Baccarelli - Heredity, 2010 - nature.com
Epigenetics investigates heritable changes in gene expression that occur without changes
in DNA sequence. Several epigenetic mechanisms, including DNA methylation and histone …

Environmental epigenetics and its implication on disease risk and health outcomes

SM Ho, A Johnson, P Tarapore, V Janakiram… - ILAR …, 2012 - academic.oup.com
This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …

Epigenomics in environmental health

BC Christensen, CJ Marsit - Frontiers in genetics, 2011 - frontiersin.org
This review considers the emerging relationships between environmental factors and
epigenetic alterations and the application of genome-wide assessments to better define …

Epigenetics and environmental exposures

RA Stein - J Epidemiol Community Health, 2012 - jech.bmj.com
It is becoming increasingly apparent that genetic factors are inadequate to fully explain
many processes that shape development and disease. For example, monozygotic twin pairs …

Environmentally induced epigenetic toxicity: potential public health concerns

EL Marczylo, MN Jacobs, TW Gant - Critical reviews in toxicology, 2016 - Taylor & Francis
Throughout our lives, epigenetic processes shape our development and enable us to adapt
to a constantly changing environment. Identifying and understanding environmentally …