The underlying pathologies of psychiatric disorders, which cause substantial personal and
social losses, remain unknown, and their elucidation is an urgent issue. To clarify the core …

Big Data has been a buzzword in almost every possible field during the last few years. The
rapid integration of massive amounts of information from diverse sources fed the hope for a …

Highlights•The combination of data-driven machine learning and theory-driven
computational models holds great promise for psychiatry.•Machine-learning analyses of …

For the first time in history, it is possible to study human behavior on great scale and in fine
detail simultaneously. Online services and ubiquitous computational devices, such as …

In the past decades, cutting-edge research techniques have facilitated better understanding
of the bi-directional 'vectors of influence'that link the genes, brain and social behavior. This …

Psychiatry research has long experienced a stagnation stemming from a lack of
understanding of the neurobiological underpinnings of phenomenologically defined mental …

Neurological diseases are on the rise worldwide, leading to increased healthcare costs and
diminished quality of life in patients. In recent years, Big Data has started to transform the …

A growing body of evidence now suggests that precision psychiatry, an interdisciplinary field
of psychiatry, precision medicine, and pharmacogenomics, serves as an indispensable …

Reproducibility is one of the most important issues for generalizing the results of clinical
research; however, low reproducibility in neuroimaging studies is well known. To overcome …

Background Psychiatric science remains descriptive, with a categorical nosology intended to
enhance interobserver reliability. Increased awareness of the mismatch between categorical …