Introduction: Myocardial infarction (MI), the most prevalent ischemic heart disease,
constitutes a primary cause of global cardiovascular disease with incidence and mortality …

Background The pathogenesis of myocardial ischemia/reperfusion is complex, involving
multiple regulatory genes and environmental factors, and requiring the simultaneous …

Context Xinbao pill (XBW), a traditional Chinese herbal formula, is widely used in clinical
treatment for cardiovascular diseases; however, the therapeutic effect of XBW on myocardial …

Panax quinquefolium saponin (PQS) alleviates hypoxia-reoxygenation injury of
cardiomyocytes in vitro by inhibiting excessive endoplasmic reticulum stress (ERS)–related …

Ischemic heart disease is one of the biggest threats to human life in the world. Reperfusion
therapy is an effective strategy to reduce infarct size and ischemic injury. However …

Myocardial infarction (MI) increased reactive oxygen species (ROS) and cardiomyocyte
apoptosis. Saponins from Panax japonicus (SPJ) exerted beneficially cardioprotective …

Plumbagin (PLB) has been previously reported to alleviate myocardial ischemia/reperfusion
injury in vivo. In the present study, the potential of plumbagin to protect against hydrogen …

New Findings What is the central question of this study? In a rat model of acute myocardial
infarction (AMI), we investigated the effect of Tongxinluo (TXL) treatment. Does TXL activate …

AIM OF THIS STUDY: The panax notoginseng saponins (PNS) have been clinically used for
the treatment of cardiovascular diseases and stroke in China. Evidences demonstrated that …

Danshen has been used in traditional Chinese medicine for hundreds of years to treat
cardiovascular diseases. However, its precise cardioprotective components and the …