Atherosclerosis is a chronic inflammatory disease promoted by hyperlipidemia. Several
studies support FOXP3-positive regulatory T cells (Tregs) as inhibitors of atherosclerosis; …

OBJECTIVE: Regulatory T cells are crucial for immune homeostasis and an impaired
regulatory T cell function results in many pathological conditions. Regulatory T cells have …

Objective—Regulatory T cells (Tregs) protect against atherosclerosis in experimental
models, but their association with cardiovascular disease in humans remains to be …

Background T cell mediated inflammation contributes to atherogenesis and the onset of
acute cardiovascular disease. Effector T cell functions are under a tight control of a …

Inflammation is essential in the initial development and progression of many cardiovascular
diseases involving innate and adaptive immune responses. The role of CD4+ CD25+ …

OBJECTIVES: Regulatory T (Treg) cells have been shown to play a protective role in
experimental atherosclerosis. However, it is unclear whether Tregs can protect from rupture …

Regulatory T cells (Tregs) express the lineage-defining transcription factor FoxP3 and play
crucial roles in self-tolerance and immune homeostasis. Thymic tTregs are selected based …

Hypercholesterolemia promotes the inflammation against lipoproteins in atherosclerosis.
Development of atherosclerosis is affected by the balance between pro-inflammatory …

Objective—Naturally occurring CD4+ CD25+ regulatory T cells (Tregs) exert suppressive
effects on effector CD4 cells and downregulate experimental autoimmune disorders. We …

Regulatory T cells (Tregs) play an important role in the regulation of T-cell–mediated
immune responses through suppression of T-cell proliferation and secretion of inhibitory …