Arterial stiffness is associated with adipokine dysregulation in non-hypertensive obese mice
M Gil-Ortega, M Martín-Ramos, SM Arribas… - Vascular …, 2016 - Elsevier
The aim of this study was to characterize alterations in vascular structure and mechanics in
murine mesenteric arteries from obese non-hypertensive mice, as well as their relationship …
murine mesenteric arteries from obese non-hypertensive mice, as well as their relationship …
Obesity Induces Artery‐Specific Alterations: Evaluation of Vascular Function and Inflammatory and Smooth Muscle Phenotypic Markers
AG Soares, MHC Carvalho… - BioMed research …, 2017 - Wiley Online Library
Vascular alterations are expected to occur in obese individuals but the impact of obesity
could be different depending on the artery type. We aimed to evaluate the obesity effects on …
could be different depending on the artery type. We aimed to evaluate the obesity effects on …
Cellular and molecular mechanisms of arterial stiffness associated with obesity
JA Leopold - Hypertension, 2013 - Am Heart Assoc
1004 Hypertension December 2013 the present study. 6 This may occur as a result of
mineralocorticoid receptor activation, which increases cellular water content and stiffness …
mineralocorticoid receptor activation, which increases cellular water content and stiffness …
Adipokines and arterial stiffness in obesity
Adipokines are active molecules with pleiotropic effects produced by adipose tissue and
involved in obesity-related metabolic and cardiovascular diseases. Arterial stiffness, which is …
involved in obesity-related metabolic and cardiovascular diseases. Arterial stiffness, which is …
Obesity and arterial compliance alterations
AM Seifalian, TD Filippatos, J Joshi… - Current vascular …, 2010 - ingentaconnect.com
Obesity is associated with increased cardiovascular disease (CVD) risk, especially when
excess body fat is distributed preferentially within the abdominal region. Obese subjects …
excess body fat is distributed preferentially within the abdominal region. Obese subjects …
Impaired myogenic tone in mesenteric arteries from overweight rats
KL Sweazea, BR Walker - Nutrition & metabolism, 2012 - Springer
Background Rats fed high fat (HFD) or high sucrose (HSD) diets develop increased
adiposity as well as impaired vasodilatory responsiveness stemming from oxidative stress …
adiposity as well as impaired vasodilatory responsiveness stemming from oxidative stress …
Loss of compliance in small arteries, but not in conduit arteries, after 6 weeks exposure to high fat diet
Arterial stiffness is a key marker in metabolic diseases and can be evaluated by arterial
compliance. Most compliance measurements are performed in large conduit arteries in …
compliance. Most compliance measurements are performed in large conduit arteries in …
Molecular Mechanisms of Adiponectin‐Induced Attenuation of Mechanical Stretch‐Mediated Vascular Remodeling
CM Ghantous, R Farhat, L Djouhri… - Oxidative medicine …, 2020 - Wiley Online Library
Hypertension induces vascular hypertrophy, which changes blood vessels structurally and
functionally, leading to reduced tissue perfusion and further hypertension. It is also …
functionally, leading to reduced tissue perfusion and further hypertension. It is also …
Cellular mechanisms underlying obesity-induced arterial stiffness
AR Aroor, G Jia, JR Sowers - American Journal of …, 2018 - journals.physiology.org
Obesity is an emerging pandemic driven by consumption of a diet rich in fat and highly
refined carbohydrates (a Western diet) and a sedentary lifestyle in both children and adults …
refined carbohydrates (a Western diet) and a sedentary lifestyle in both children and adults …
Regulation of vascular smooth muscle tone by adipose-derived contracting factor
Obesity and arterial hypertension, important risk factors for atherosclerosis and coronary
artery disease, are characterized by an increase in vascular tone. While obesity is known to …
artery disease, are characterized by an increase in vascular tone. While obesity is known to …