Histone acetylation recruits the SWR1 complex to regulate active DNA demethylation in Arabidopsis

WF Nie, M Lei, M Zhang, K Tang… - Proceedings of the …, 2019 - National Acad Sciences
Active DNA demethylation is critical for controlling the DNA methylomes in plants and
mammals. However, little is known about how DNA demethylases are recruited to target loci …

The DNA demethylase ROS1 targets genomic regions with distinct chromatin modifications

K Tang, Z Lang, H Zhang, JK Zhu - Nature plants, 2016 - nature.com
Abstract The Arabidopsis ROS1/DEMETER family of 5-methylcytosine (5mC) DNA
glycosylases are the first genetically characterized DNA demethylases in eukaryotes …

[HTML][HTML] SRA-domain proteins required for DRM2-mediated de novo DNA methylation

LM Johnson, JA Law, A Khattar, IR Henderson… - PLoS …, 2008 - journals.plos.org
De novo DNA methylation and the maintenance of DNA methylation in asymmetrical
sequence contexts is catalyzed by homologous proteins in plants (DRM2) and animals …

[HTML][HTML] SIZ1-mediated SUMOylation of ROS1 enhances its stability and positively regulates active DNA demethylation in Arabidopsis

X Kong, Y Hong, YF Hsu, H Huang, X Liu, Z Song… - Molecular plant, 2020 - cell.com
The 5-methylcytosine DNA glycosylase/lyase REPRESSOR OF SILENCING 1 (ROS1)-
mediated active DNA demethylation is critical for shaping the genomic DNA methylation …

A novel protein complex that regulates active DNA demethylation in Arabidopsis

P Liu, WF Nie, X Xiong, Y Wang, Y Jiang… - Journal of Integrative …, 2021 - Wiley Online Library
Active DNA demethylation is critical for altering DNA methylation patterns and regulating
gene expression. The 5‐methylcytosine DNA glycosylase/lyase ROS1 initiates a base …

[HTML][HTML] DDM1 and Lsh remodelers allow methylation of DNA wrapped in nucleosomes

DB Lyons, D Zilberman - Elife, 2017 - elifesciences.org
Cytosine methylation regulates essential genome functions across eukaryotes, but the
fundamental question of whether nucleosomal or naked DNA is the preferred substrate of …

[HTML][HTML] The Arabidopsis nucleosome remodeler DDM1 allows DNA methyltransferases to access H1-containing heterochromatin

A Zemach, MY Kim, PH Hsieh, D Coleman-Derr… - Cell, 2013 - cell.com
Nucleosome remodelers of the DDM1/Lsh family are required for DNA methylation of
transposable elements, but the reason for this is unknown. How DDM1 interacts with other …

[HTML][HTML] The developmental regulator PKL is required to maintain correct DNA methylation patterns at RNA-directed DNA methylation loci

R Yang, Z Zheng, Q Chen, L Yang, H Huang, D Miki… - Genome Biology, 2017 - Springer
Background The chromodomain helicase DNA-binding family of ATP-dependent chromatin
remodeling factors play essential roles during eukaryote growth and development. They are …

[HTML][HTML] The methyl-CpG-binding protein MBD7 facilitates active DNA demethylation to limit DNA hyper-methylation and transcriptional gene silencing

Z Lang, M Lei, X Wang, K Tang, D Miki, H Zhang… - Molecular cell, 2015 - cell.com
DNA methylation is a conserved epigenetic mark that plays important roles in plant and
vertebrate development, genome stability, and gene regulation. Canonical Methyl-CpG …

[HTML][HTML] Interplay between Active Chromatin Marks and RNA-Directed DNA Methylation in Arabidopsis thaliana

MVC Greenberg, A Deleris, CJ Hale, A Liu, S Feng… - PLoS …, 2013 - journals.plos.org
DNA methylation is an epigenetic mark that is associated with transcriptional repression of
transposable elements and protein-coding genes. Conversely, transcriptionally active …