68Ga-labeled peptides in tumor imaging

HR Maecke, M Hofmann… - Journal of Nuclear …, 2005 - Soc Nuclear Med
Radiolabeled peptides are of increasing interest in nuclear oncology. Special emphasis has
been given to the development of peptides labeled with positron emitters. Among these, 68 …

68Ga-PET Radiopharmacy: A Generator-Based Alternative to 18F-Radiopharmacy

HR Maecke, JP André - PET chemistry: the driving force in molecular …, 2007 - Springer
Positron emission tomography (PET) is becoming a dominating method in the field of
molecular imaging. Most commonly used radionuclides are accelerator produced 11 C and …

68Ga-labelled DOTA-derivatised peptide ligands

GJ Meyer, H Mäcke, J Schuhmacher… - European journal of …, 2004 - Springer
Abstract 68 Ge/68 Ga generators provide cyclotron-independent access to positron emission
tomography (PET) radiopharmaceuticals. We describe a system which allows the safe and …

Radiolabelling DOTA-peptides with 68Ga

WAP Breeman, M de Jong, E de Blois… - European journal of …, 2005 - Springer
Purpose A new field of interest is the application of 68 Ga-labelled DOTA-conjugated
peptides for positron emission tomography (PET). The commercially available or house …

The importance of high specific radioactivity in the performance of 68Ga-labeled peptide

I Velikyan, GJ Beyer, E Bergström-Pettermann… - Nuclear medicine and …, 2008 - Elsevier
The use of 68Ga-labeled peptides in diagnosis, dosimetry, therapy planning and follow-up
of response to chemo-and radiotherapy requires accurate quantification of tracer binding …

Radiolabeling of DOTA-like conjugated peptides with generator-produced 68Ga and using NaCl-based cationic elution method

D Mueller, WAP Breeman, I Klette, M Gottschaldt… - Nature protocols, 2016 - nature.com
Abstract Gallium-68 (68 Ga) is a generator-produced radionuclide with a short half-life (t ½=
68 min) that is particularly well suited for molecular imaging by positron emission …

68Ga‐PET: a powerful generator‐based alternative to cyclotron‐based PET radiopharmaceuticals

M Fani, JP André, HR Maecke - Contrast media & molecular …, 2008 - Wiley Online Library
PET (positron emission tomography) is a powerful diagnostic and imaging technique which
requires short‐lived positron emitting isotopes. The most commonly used are accelerator …

A fully automated synthesis for the preparation of 68Ga-labelled peptides

C Decristoforo, R Knopp… - Nuclear medicine …, 2007 - journals.lww.com
Background Generator-produced 68 Ga has attracted increasing interest for radiolabelling
peptides used in PET applications. So far, the synthesis of 68 Ga-peptide …

Comparative gallium-68 labeling of TRAP-, NOTA-, and DOTA-peptides: practical consequences for the future of gallium-68-PET

J Notni, K Pohle, HJ Wester - EJNMMI research, 2012 - Springer
Abstract Background Currently, 68 Ga-labeled 1, 4, 7, 10-tetraazacyclododecane-tetraacetic
acid (DOTA)-peptides are the most widely used class of 68 Ga radiotracers for PET …

Microwave-Supported Preparation of 68Ga Bioconjugates with High Specific Radioactivity

I Velikyan, GJ Beyer, B Långström - Bioconjugate chemistry, 2004 - ACS Publications
The generator-produced positron-emitting 68Ga (T 1/2= 68 min) is of potential interest for
clinical PET. 68Ga as a metallic cation is suitable for complexation reactions with chelators …