Tuberculosis-associated microRNAs: from pathogenesis to disease biomarkers

A Sinigaglia, E Peta, S Riccetti, S Venkateswaran… - Cells, 2020 - mdpi.com
Tuberculosis (TB) caused by Mycobacterium tuberculosis is one of the most lethal infectious
diseases with estimates of approximately 1.4 million human deaths in 2018. M. tuberculosis …

miRNAs in tuberculosis: new avenues for diagnosis and host-directed therapy

N Sabir, T Hussain, SZA Shah, A Peramo… - Frontiers in …, 2018 - frontiersin.org
Tuberculosis (TB) is one of the most fatal infectious diseases and a leading cause of
mortality, with 95% of these deaths occurring in developing countries. The causative agent …

MicroRNAs as immune regulators and biomarkers in tuberculosis

L Wang, Y Xiong, B Fu, D Guo, MY Zaky, X Lin… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb), is one of the most
lethal infectious disease worldwide, and it greatly affects human health. Some diagnostic …

miRNAs in immune responses to Mycobacterium tuberculosis infection

T Yang, B Ge - Cancer letters, 2018 - Elsevier
Tuberculosis (TB) is one of the most fatal infectious diseases, affecting one third of the
world's population. The causative agent, Mycobacterium tuberculosis (Mtb), has a well …

Unraveling the role of microRNAs in Mycobacterium tuberculosis infection and disease: advances and pitfalls

C Ruiz-Tagle, R Naves, ME Balcells - Infection and Immunity, 2020 - Am Soc Microbiol
Tuberculosis (TB) is an infectious disease of extremely high epidemiological burden
worldwide that is easily acquired through the inhalation of infected respiratory droplets. The …

The Role of microRNAs and Long Non-Coding RNAs in the Regulation of the Immune Response to Mycobacterium tuberculosis Infection

M Kundu, J Basu - Frontiers in immunology, 2021 - frontiersin.org
Non-coding RNAs have emerged as critical regulators of the immune response to infection.
MicroRNAs (miRNAs) are small non-coding RNAs which regulate host defense mechanisms …

microRNA as biomarkers in tuberculosis: a new emerging molecular diagnostic solution

P Agrawal, A Upadhyay, A Kumar - Diagnostic Microbiology and Infectious …, 2023 - Elsevier
Tuberculosis (TB) caused by Mycobacterium tuberculosis is a lethal infectious disease that
is prevalent worldwide. MicroRNAs are small, non-coding RNA molecules that show a …

Monocyte and macrophage miRNA: potent biomarker and target for host-directed therapy for tuberculosis

P Sampath, KM Periyasamy, UD Ranganathan… - Frontiers in …, 2021 - frontiersin.org
The end TB strategy reinforces the essentiality of readily accessible biomarkers for early
tuberculosis diagnosis. Exploration of microRNA (miRNA) and pathway analysis opens an …

Immunomodulating microRNAs of mycobacterial infections

P Bettencourt, D Pires, E Anes - Tuberculosis, 2016 - Elsevier
MicroRNAs are a class of small non-coding RNAs that have emerged as key regulators of
gene expression at the post-transcriptional level by sequence-specific binding to target …

Host-directed therapy of tuberculosis: what is in it for microRNA?

M Iannaccone, A Dorhoi… - Expert opinion on …, 2014 - Taylor & Francis
Tuberculosis (TB) is a major health threat and current intervention measures are far from
satisfactory. MicroRNAs (miRs) have become major targets of investigations for different …