To overcome cancer-associated immunosuppression, we prepared a dual-targeting vector
to deliver CpG oligodeoxynucleotides (ODN) to macrophages. The dual-targeting system …

To efficiently deliver CpG oligodeoxynucleotides (ODNs) to macrophages for the reversal of
cancer-induced immunosuppression, nanoparticles ODN@ MCBSA with mannosylated …

To efficiently deliver CpG oligodeoxynucleotides (ODN) in cancer immunotherapy, a
multifunctional macrophage targeting delivery system was designed and prepared …

Immunotherapy has achieved prominent clinical efficacy in combating cancer and has
recently become a mainstream treatment strategy. However, achieving broad efficacy with a …

Certain chemotherapeutics can induce tumor cells' immunogenic cell death (ICD), release
tumor antigens, and thereby trigger personalized antitumor immune responses. Co-delivery …

Therapeutic nucleic acid delivery to solid tumors remains a challenge due to enzymatic
degradation in cellular uptake and endosomal escape process as well as limited cell …

Among approaches of current cancer immunotherapy, a dendritic cell (DC)-targeted vaccine
based on nanotechnology could be a promising way to efficiently induce potent immune …

Adoptive cell therapy by natural cells for drug delivery has achieved encouraging progress
in cancer treatment over small‐molecule drugs. Macrophages have a great potential in …

In this study, we report on polymer nanoparticles (NPs) that can induce an enhanced
immune response in dendritic cell (DC)-based cancer immunotherapy by the combined …

Cancer evolves to evade or compromise the surveillance of the immune system, and cancer
immunotherapy aims to harness the immune system in order to inhibit cancer development …