Most genes are expressed from both parental chromosomes; however, a small number of
genes in mammals are imprinted and expressed in a parent-of-origin specific manner …

Imprinted genes represent a curious defiance of normal Mendelian genetics. Mammals
inherit two complete sets of chromosomes, one from the mother and one from the father, and …

Imprinted genes have been associated with a wide range of diseases. Many of these
diseases have symptoms that can be understood in the context of the evolutionary forces …

Genomic imprinting is the phenomenon where the expression of a locus differs between the
maternally and paternally inherited alleles. Typically, this manifests as transcriptional …

Genomic imprinting affects several dozen mammalian genes and results in the expression of
those genes from only one of the two parental chromosomes. This is brought about by …

Imprinting results in the preferential expression of either the maternal or the paternal allele of
certain genes, and has a critical influence on the regulation of mammalian development …

Imprinted genes are expressed specifically from one or other parental allele. Over 70 are
now known, and about one-half of these are expressed from the paternal allele and one-half …

Genomic imprinting, a process of epigenetic modification which allows the gene to be
expressed in a parent-of-origin specific manner, has an essential role in normal growth and …

Genomic imprinting refers to an epigenetic marking of genes that results in monoallelic
expression. This parent-of-origin dependent phenomenon is a notable exception to the laws …

▪ Abstract An intriguing characteristic of imprinted genes is that they often cluster in large
chromosomal domains, raising the possibility that gene-specific and domain-specific …