Background Clinical studies demonstrated peripheral nociceptor deficit in stress‐related
chronic pain states, such as fibromyalgia. The interactions of stress and nociceptive systems …

Whereas acute stress often results in analgesia, chronic stress can trigger
hyperalgesia/allodynia. This influence of long-term stress on nociception is relevant to …

The perception and response to pain are severely impacted by exposure to stressors. In
some animal models, stress increases pain sensitivity, which is termed stress-induced …

Stress affects brain activity and promotes long-term changes in multiple neural systems.
Exposure to stressors causes substantial effects on the perception and response to pain. In …

Exposure to stressors causes substantial effects on the perception and response to pain. In
several animal models, chronic stress produces hyperalgesia. The insular (IC) and anterior …

The single application of high-concentration of capsaicin has been used as an analgesic
therapy of persistent pain. However, its effectiveness and underlying mechanisms remain to …

Repeated cold stress (RCS) can trigger the development of fibromyalgia (FM)-like
symptoms, including persistent deep-tissue pain, although nociceptive changes to the skin …

In the present study, the presence of an endogenous capsaicin-like substance and the role
of capsaicin receptors in nociception during inflammation were assessed using Fos …

To characterize the role of capsaicin-sensitive primary afferents in inflammatory pain, the
effects of subcutaneous (sc) injection of 0.15% capsaicin on different chemical irritants …

To address the mechanisms of hyperalgesia and dorsal horn plasticity following peripheral
tissue inflammation, the effects of adjuvant-induced inflammation of the rat hindpaw on …