Rutin ameliorates metabolic acidosis and fibrosis in alloxan induced diabetic nephropathy and cardiomyopathy in experimental rats

D Ganesan, A Albert, E Paul… - Molecular and cellular …, 2020 - Springer
Diabetic nephropathy and cardiomyopathy are two major causes of mortality among patients
with diabetes mellitus (DM). Since current diabetic medications are associated with various …

[HTML][HTML] Combination of ramipril and rutin alleviate alloxan induced diabetic nephropathy targeting multiple stress pathways in vivo

D Ganesan, A Holkar, A Albert, E Paul… - Biomedicine & …, 2018 - Elsevier
Diabetic nephropathy (DN) is considered as one of the major microvascular complications of
diabetes mellitus (DM) which leads to end stage renal disease (ESRD). Even though …

Rutin administration attenuates myocardial dysfunction in diabetic rats

JFC Guimaraes, BP Muzio, CM Rosa… - Cardiovascular …, 2015 - Springer
Background Oxidative stress plays a major role in diabetic cardiomyopathy pathogenesis.
Anti-oxidant therapy has been investigated in preventing or treating several diabetic …

Cardioprotective effects of rutin via alteration in TNF-α, CRP, and BNP levels coupled with antioxidant effect in STZ-induced diabetic rats

R Saklani, SK Gupta, IR Mohanty, B Kumar… - Molecular and cellular …, 2016 - Springer
Diabetic cardiomyopathy (DCM) is a dreadful complication of diabetes responsible for 80%
mortality in diabetic patients, but unfortunately its pharmacotherapy is still incomplete. Rutin …

Fenugreek attenuation of diabetic nephropathy in alloxan-diabetic rats: attenuation of diabetic nephropathy in rats

AAR Sayed, M Khalifa, FF Abd el-Latif - Journal of physiology and …, 2012 - Springer
Diabetic nephropathy is a major cause of morbidity and mortality in diabetic patients. To
prevent the development of this disease and to improve advanced kidney injury, effective …

Chamomile and oregano extracts synergistically exhibit antihyperglycemic, antihyperlipidemic, and renal protective effects in alloxan-induced diabetic rats

R Prasanna, EA Ashraf… - Canadian journal of …, 2017 - cdnsciencepub.com
The bio-activities of separate Matricaria chamomilla (chamomile) and Origanum vulgare
(oregano) are well studied; however, the combined effects of both natural products in animal …

Rutin alleviates diabetic cardiomyopathy in a rat model of type 2 diabetes

YB Wang, ZM Ge, WQ Kang… - Experimental and …, 2015 - spandidos-publications.com
Diabetic cardiomyopathy (DCM), an independent coronary heart disease that develops in
diabetic individuals, is characterized by changes in the myocardial structure and function …

Influence of rutin treatment on biochemical alterations in experimental diabetes

AAH Fernandes, ELB Novelli, K Okoshi… - Biomedicine & …, 2010 - Elsevier
Dietary antioxidant compounds such as flavonoids may offer some protection against early-
stage diabetes mellitus and its complications. Abnormalities in both glucose metabolism and …

[HTML][HTML] Allium tuberosum alleviates diabetic nephropathy by supressing hyperglycemia-induced oxidative stress and inflammation in high fat diet/streptozotocin …

Z Ni, L Guo, F Liu, OJ Olatunji, M Yin - Biomedicine & pharmacotherapy, 2019 - Elsevier
The objective of this study was to evaluate the effect of the butanol fraction from Allium
tuberosum (BFAT) in high fat diet/streptozotocin (HFD/STZ) induced diabetic nephropathy …

[PDF][PDF] Effect of Terminalia arjuna stem bark on antioxidant status in liver and kidney of alloxan diabetic rats

B Raghavan, SK Kumari - Indian Journal of Physiology and Pharmacology, 2006 - ijpp.com
Free radicals and associated oxidative stress induced by alloxan are implicated in eliciting
pathological changes in diabetes mellitus. Terminalia arjuna bark, an indigenous plant used …