The cross-talk between mesenchymal stem and stromal cells (MSCs) and macrophages is
critical for the restoration of tissue homeostasis after injury. Here, we demonstrate a pathway …

Amphiregulin (AREG), which acts as one of the ligands for epidermal receptor growth factor
receptor (EGFR), plays a crucial role in tissue repair, inflammation, and immunity. AREG is …

The epidermal growth factor receptor ligand Amphiregulin has a well-documented role in the
restoration of tissue homeostasis after injury; however, the mechanism by which …

Mesenchymal stem cells (MSCs) are a group of fibroblast-like multipotent mesenchymal
stromal cells that have the ability to differentiate into osteoblasts, adipocytes, and …

Purpose: To explore the role and mechanism of bone marrow–derived mesenchymal stem
cells (BM-MSCs) in corneal epithelial wound healing in type 1 diabetic mice. Methods …

Macrophages are crucial drivers of inflammatory corneal neovascularization and thus are
potential targets for immunomodulatory therapies. We hypothesized that therapeutic use of …

Mesenchymal stem cells (MSCs) are speculated to act at macrophage-injury interfaces to
mediate efficient repair. To explore this facet in-depth this study evaluates the influence of …

Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …

Intravenously administered mesenchymal stem/stromal cells (MSCs) engraft only transiently
in recipients, but confer long-term therapeutic benefits in patients with immune disorders …

Mesenchymal stromal cells (MSCs) are a promising therapeutic option for multiple immune
diseases/disorders; however, efficacy of MSC treatments can vary significantly. We present a …