A Glu487Lys polymorphism in the gene for mitochondrial aldehyde dehydrogenase 2 is associated with myocardial infarction in elderly Korean men

SA Jo, EK Kim, MH Park, C Han, HY Park, Y Jang… - Clinica chimica acta, 2007 - Elsevier
BACKGROUND: A homozygous mutant (ALDH2⁎ 2/⁎ 2) of the gene for mitochondrial
aldehyde dehydrogenase 2 (ALDH2) at codon 487 was reported to be associated with …

ALDH2 gene G487A polymorphism and coronary artery disease: a meta‐analysis including 5644 participants

Y Li, H Wang, J Wu, HJ Kim, X Yang… - Journal of cellular …, 2018 - Wiley Online Library
Several studies indicate the mitochondrial Aldehyde Dehydrogenase‐2 (ALDH 2) gene
G487A polymorphism may be correlated with coronary artery disease (CAD) susceptibility …

ALDH2 rs671 Polymorphism and Coronary Heart Disease Risk Among Asian Populations: A Meta-Analysis and Meta-Regression

Q Wang, S Zhou, L Wang, M Lei, Y Wang… - DNA and cell …, 2013 - liebertpub.com
Mitochondrial aldehyde dehydrogenase-2 (ALDH2) is the principal enzyme involved in
alcohol metabolism in humans. Emerging evidence has shown that the common rs671 G> A …

Aldehyde dehydrogenase 2 gene is a risk factor for myocardial infarction in Japanese men

S Takagi, N Iwai, R Yamauchi, S Kojima… - Hypertension …, 2002 - jstage.jst.go.jp
In epidemiological studies, moderate alcohol consumption has been consistently associated
with a reduced risk of myocardial infarction (MI). About half of Japanese show an extremely …

The ALDH2 Glu504Lys polymorphism is associated with coronary artery disease in Han Chinese: Relation with endothelial ADMA levels

YJ Guo, L Chen, YP Bai, L Li, J Sun, GG Zhang… - Atherosclerosis, 2010 - Elsevier
OBJECTIVES: We studied the association between mitochondrial aldehyde dehydrogenase
(ALDH2) Glu504Lys (rs671 or ALDH2* 2) polymorphism and coronary artery disease (CAD) …

Variant Aldehyde Dehydrogenase 2 (ALDH2*2) Is a Risk Factor for Coronary Spasm and ST‐Segment Elevation Myocardial Infarction

Y Mizuno, S Hokimoto, E Harada… - Journal of the …, 2016 - Am Heart Assoc
Background Mitochondrial aldehyde dehydrogenase 2 (ALDH 2) plays a key role in
removing toxic aldehydes. Deficient variant ALDH 2* 2 genotype is prevalent in up to 40% of …

Epidemiologic study of the association of low-Km mitochondrial acetaldehyde dehydrogenase genotypes with blood pressure level and the prevalence of …

K Amamoto, T Okamura, S Tamaki, Y Kita… - Hypertension …, 2002 - jstage.jst.go.jp
Abstract In Japanese and other Asians, the prevalence of genetically decreased
mitochondrial aldehyde dehydrogenase (ALDH2) activity is higher than in Caucasians. The …

Association between aldehyde dehydrogenase 2 genetic polymorphism and serum lipids or lipoproteins: a meta-analysis of seven East Asian populations

PP Hao, L Xue, XL Wang, YG Chen… - …, 2010 - atherosclerosis-journal.com
Moderate alcohol consumption appears to confer some protection against coronary heart
disease, which is related to changes in serum levels of lipoproteins, especially high-density …

The polymorphism in acetaldehyde dehydrogenase 2 gene, causing a substitution of Glu> Lys504, is not associated with coronary atherosclerosis severity in Han …

F Xu, YG Chen, YJ Geng, H Zhang… - The Tohoku Journal of …, 2007 - jstage.jst.go.jp
Severity in Han Chinese. Tohoku J. Exp. Med., 2007, 213 (3), 215-220── Alcohol
consumption has an important effect on coronary atherosclerotic heart disease (CAD) …

[PDF][PDF] Aldehyde dehydrogenase 2 (ALDH2) polymorphism gene and coronary artery disease risk: a meta-analysis

LL Zhang, YQ Wang, B Fu, SL Zhao, Y Kui - Genet Mol Res, 2015 - m.jstshuichan.com
We studied the association between aldehyde dehydrogenase 2 (ALDH2) polymorphism
and coronary artery disease (CAD) and clarified the mechanisms underlying this …