The decline in age at puberty in the general population has been paralleled by an increase
in the number of girls referred for evaluation of precocious puberty (PP). In 1999, The …

Although precocious puberty has standard clinical definitions and diagnostic tests are
improving, the management of children who have signs of early puberty has become more …

Delayed puberty (DP) is defined as the lack of pubertal development by an age that is 2–2.5
SDs beyond the population mean. Although it generally represents a normal variant in …

OBJECTIVE. Using basal specimens from original gonadotropin radioimmunoassays, it was
not possible to differentiate prepuberty from puberty hence gonadotropin-releasing hormone …

Previously used standards for the diagnosis of precocious puberty in girls no longer appear
to be appropriate in the USA, in that a significant number of girls are being seen in …

Objective. The Lawson Wilkins Pediatric Endocrine Society recently issued new
recommendations for the age at which puberty should be considered precocious, lowering …

In this issue of JCEM, Palmert et al.(see page 415)(1), address the issue of whether all
children with precocious puberty need treatment by reporting long-term follow-up data on 20 …

Since the early 1980s, the focus on the importance of puberty to adolescent development
has continued with variability in the methodology selected to measure puberty. To capture …

Objective The mainstay of distinction between prepubertal girls and girls who are suspected
of having central precocious puberty (CPP) is based on gonadotropin measurements after a …

Objective: A decrease in age at pubertal onset has been observed internationally. The aim
of this study was to describe a large cohort of Caucasian girls referred with signs of early …