The interest in vitamin D continues unabated with thousands of publications contributing to a
vast and growing literature each year. It is widely recognized that the vitamin D receptor …

Context Vitamin D is classically recognized as a regulator of calcium and phosphorus
metabolism. Recent advances in the measurement of vitamin D metabolites, diagnosis of …

Abstract The 2 nd International Conference on Controversies in Vitamin D was held in
Monteriggioni (Siena), Italy, September 11-14, 2018. The aim of this meeting was to address …

Significant controversy has emerged over the last decade concerning the effects of vitamin D
on skeletal and nonskeletal tissues. The demonstration that the vitamin D receptor is …

The growing attention to the role of vitamin D in skeletal and extra-skeletal diseases over the
last decade induced an increased demand for vitamin D determination as well as a dramatic …

The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

The role of vitamin D in maintaining bone health has been known for decades. Recently,
however, the discovery that many tissues expressed the vitamin D receptor and were able to …

The discovery of the vitamin D endocrine system and a receptor for the hormonal form, 1α,
25-dihydroxyvitamin D3, has brought a new understanding of the relationship between …

The past decade, particularly the last 18 months, witnessed a vigorous increase in interest in
vitamin D from both the lay and biomedical worlds. Much of the growing interest in vitamin D …

Vitamin D is a fat-soluble hormone that traditionally has been linked to bone health.
Recently, its involvement has been extended to other (extra-skeletal) disease areas, such as …