Long noncoding RNA: genome organization and mechanism of action

VS Akhade, D Pal, C Kanduri - Long Non Coding RNA Biology, 2017 - Springer
For the last four decades, we have known that noncoding RNAs maintain critical
housekeeping functions such as transcription, RNA processing, and translation. However, in …

Posttranscriptional gene regulation by long noncoding RNA

JH Yoon, K Abdelmohsen, M Gorospe - Journal of molecular biology, 2013 - Elsevier
Eukaryotic cells transcribe a vast number of noncoding RNA species. Among them, long
noncoding RNAs (lncRNAs) have been widely implicated in the regulation of gene …

Long noncoding RNAs: emerging stars in gene regulation, epigenetics and human disease

A Bhan, SS Mandal - ChemMedChem, 2014 - Wiley Online Library
Noncoding RNAs (ncRNAs) are classes of transcripts that are encoded by the genome and
transcribed but never get translated into proteins. Though not translated into proteins …

RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts

S Geisler, J Coller - Nature reviews Molecular cell biology, 2013 - nature.com
The increased application of transcriptome-wide profiling approaches has led to an
explosion in the number of documented long non-coding RNAs (lncRNAs). While these new …

Decoding the function of nuclear long non-coding RNAs

LL Chen, GG Carmichael - Current opinion in cell biology, 2010 - Elsevier
Long non-coding RNAs (lncRNAs) are mRNA-like, non-protein-coding RNAs that are
pervasively transcribed throughout eukaryotic genomes. Rather than silently accumulating …

Long noncoding RNAs: an emerging link between gene regulation and nuclear organization

S Quinodoz, M Guttman - Trends in cell biology, 2014 - cell.com
Mammalian genomes encode thousands of long noncoding RNAs (lncRNAs) that play
important roles in diverse biological processes. As a class, lncRNAs are generally enriched …

Long non-coding RNAs in the cytoplasm

F Rashid, A Shah, G Shan - Genomics, proteomics and …, 2016 - academic.oup.com
An enormous amount of long non-coding RNAs (lncRNAs) transcribed from eukaryotic
genome are important regulators in different aspects of cellular events. Cytoplasm is the …

Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs

VA Moran, RJ Perera, AM Khalil - Nucleic acids research, 2012 - academic.oup.com
The recent discovery that the human and other mammalian genomes produce thousands of
long non-coding RNAs (lncRNAs) raises many fascinating questions. These mRNA-like …

Long noncoding RNAs: regulation, function and cancer

A Rafiee, F Riazi-Rad, M Havaskary… - … and Genetic Engineering …, 2018 - Taylor & Francis
Long noncoding RNAs (lncRNAs) are non-protein-coding RNA transcripts that exert a key
role in many cellular processes and have potential toward addressing disease etiology …

Cellular functions of long noncoding RNAs

RW Yao, Y Wang, LL Chen - Nature cell biology, 2019 - nature.com
A diverse catalog of long noncoding RNAs (lncRNAs), which lack protein-coding potential,
are transcribed from the mammalian genome. They are emerging as important regulators in …