Reactive oxygen species (ROS) are highly reactive chemical species containing oxygen,
controlled by both enzymatic and nonenzymatic antioxidant defense systems. In the heart …

Acute and chronic excessive intracellular increase of reactive oxygen species (ROS) is
involved in the development and progression of cardiovascular diseases. ROS are by …

Reactive oxygen species (ROS) are formed at an accelerated rate in postischemic
myocardium. Cardiac myocytes, endothelial cells, and infiltrating neutrophils contribute to …

Reactive oxygen species (ROS) are subcellular messengers in gene regulatory and signal
transduction pathways. In pathological situations, ROS accumulate due to excessive …

Reactive oxygen species (ROS) are subcellular messengers in signal transductions
pathways with both beneficial and deleterious roles. ROS are generated as a by-product of …

Reactive oxygen species (ROS) are proposed to contribute to the deterioration of cardiac
function in patients with heart diseases. It has been reported that ROS are increased in the …

Ever since the discovery of free radicals, many hypotheses on the deleterious actions of
reactive oxygen species (ROS) have been proposed. However, increasing evidence …

Oxidative stress, defined as an excess production of reactive oxygen species (ROS) relative
to antioxidant defense, has been shown to play an important role in the pathophysiology of …

Oxidative stress has long been implicated in cardiovascular disease, but more recently, the
role of reactive oxygen species (ROS) in normal physiological signaling has been …

ROS are characterised by their high chemical reactivity and include both free radicals (that
is, species with one or more unpaired electrons, such as superoxide (O2. J) and hydroxyl …