Targeted therapy for head and neck cancer: signaling pathways and clinical studies
Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
Targeted therapy in head and neck cancer
SK Kundu, M Nestor - Tumor Biology, 2012 - Springer
Head and neck squamous cell carcinoma (HNSCC) of multi-factorial etiopathogenesis is
rising worldwide. Treatment-associated toxicity problems and treatment failure in advanced …
rising worldwide. Treatment-associated toxicity problems and treatment failure in advanced …
Overview of current and future biologically based targeted therapies in head and neck squamous cell carcinoma
A Matta, R Ralhan - Head & neck oncology, 2009 - Springer
Recent advances in genomics, proteomics, bioinformatics and systems biology have
unraveled the complex aberrant signaling networks in cancer. The knowledge accrued has …
unraveled the complex aberrant signaling networks in cancer. The knowledge accrued has …
Current trends and future prospects of molecular targeted therapy in head and neck squamous cell carcinoma
N Kitamura, S Sento, Y Yoshizawa, E Sasabe… - International journal of …, 2020 - mdpi.com
In recent years, advances in drug therapy for head and neck squamous cell carcinoma
(HNSCC) have progressed rapidly. In addition to cytotoxic anti-cancer agents such as …
(HNSCC) have progressed rapidly. In addition to cytotoxic anti-cancer agents such as …
Clinical update on cancer: molecular oncology of head and neck cancer
Head and neck cancers encompass a heterogeneous group of tumours that, in general, are
biologically aggressive in nature. These cancers remain difficult to treat and treatment can …
biologically aggressive in nature. These cancers remain difficult to treat and treatment can …
Head and neck cancer: from anatomy to biology
The 20th century saw great advances in anatomy‐based (surgery and radiotherapy) and
chemotherapy approaches for treating head and neck squamous cell carcinoma (HNSCC) …
chemotherapy approaches for treating head and neck squamous cell carcinoma (HNSCC) …
Emerging drugs to treat squamous cell carcinomas of the head and neck
C Fung, JR Grandis - Expert opinion on emerging drugs, 2010 - Taylor & Francis
Importance of the field: Head and neck squamous cell carcinoma (HNSCC) is the eighth
leading cause of cancer death worldwide. Despite advances in surgery and chemoradiation …
leading cause of cancer death worldwide. Despite advances in surgery and chemoradiation …
Current and emerging molecular therapies for head and neck squamous cell carcinoma
F Kordbacheh, CS Farah - Cancers, 2021 - mdpi.com
Simple Summary Next-generation sequencing of head and neck squamous cell carcinoma
has revealed multiple new gene mutations, while simultaneously confirming the role of …
has revealed multiple new gene mutations, while simultaneously confirming the role of …
Promising new molecular targeted therapies in head and neck cancer
K Dorsey, M Agulnik - Drugs, 2013 - Springer
Despite advances in multimodality therapies for the treatment of squamous cell carcinoma of
the head and neck (SCCHN), survival rates, functional outcomes and toxicities of therapy …
the head and neck (SCCHN), survival rates, functional outcomes and toxicities of therapy …
Targeted therapies for squamous cell carcinoma of the head and neck: current knowledge and future directions
Despite progress in the therapeutic management of patients with squamous cell carcinoma
of the head and neck (SCCHN), the mortality rate of patients presenting with advanced …
of the head and neck (SCCHN), the mortality rate of patients presenting with advanced …