The synthesis and release of melatonin in the brain harmonize various physiological
functions. The apparent decline in melatonin levels with advanced aging is an aperture to …

Melatonin, a hormone secreted during darkness, plays a key role in various physiological
responses including regulation of circadian rhythms, sleep homeostasis, retinal …

Preservation of sleep, a proper nutrition and adequate physical exercise are key elements
for healthy aging. Aging causes sleep alterations, and in turn, sleep disturbances lead to …

The circadian rhythm of the pineal gland hormone, melatonin is generated within the
hypothalamic suprachiasmatic nuclei (SCN), site of the circadian clock. The circadian clock …

Melatonin, the 'hormone of darkness' is a neuronal hormone secreted by the pineal gland
and other extra pineal sites. Responsible for the circadian rhythm and seasonal behaviour of …

Melatonin, a pineal gland synthesized neurohormone is known as a multifunctioning
pleiotropic agent which has a wide range of neuroprotective role in manifold age-related …

The suprachiasmatic nucleus (SCN) in hypothalamus contains a light-entrained circadian
clock, the master pacemaker that orchestrates mammalian circadian rhythms in physiology …

Melatonin is a regulator of the circadian multioscillator system. It transmits the information
'darkness', contributes to internal and external alignment of rhythms and, presumably via …

Prevention of neurodegenerative diseases is presently a major goal for our Society and
melatonin, an unusual phylogenetically conserved molecule present in all aerobic …

In mammals, a central circadian clock, located in the suprachiasmatic nuclei (SCN) of the
hypothalamus, tunes the innate circadian physiological rhythms to the ambient 24 h light …