High-grade meningiomas frequently recur and are associated with high rates of morbidity
and mortality. To determine the factors that promote the development and evolution of these …

Background Genomic studies of high-grade/progressive meningiomas have reported a
heterogeneous mutation spectrum, identifying few recurrently mutated genes. Most studies …

Meningiomas are the most common primary intracranial neoplasms in adults. Current
histopathological grading schemes do not consistently predict their natural history. Classic …

Meningiomas are one of the most common adult brain tumors. For most patients, surgical
excision is curative. However, up to 20% recur. Currently, the molecular determinants …

Meningiomas account for up to 30% of all primary intracranial tumours. They are
histologically classified according to the World Health Organization (WHO) classification of …

Although a majority of meningiomas are benign neoplasms, those occurring at the cranial
base may be challenging tumors to treat because of extensive tissue invasion, an inability to …

Meningiomas are the most common primary intracranial tumour in adults. Patients with
symptoms are generally treated with surgery as there are no effective medical therapies. The …

Meningiomas are mostly benign, slow-growing tumors of the CNS that originate from
arachnoidal cap cells. While monosomy 22 is the most frequent genetic abnormality found in …

Meningiomas, derived from arachnoid cap cells, are the most common intracranial tumor.
High-grade meningiomas, as well as those located at the skull base or near venous sinuses …

There has been a recent revolution in our understanding of the genetic factors that drive
meningioma, punctuating an equilibrium that has existed since Cushing's germinal studies …